586-60-7

• 常用中文名：达克罗宁
• 常用英文名：Dyclonine
• CAS号：586-60-7
• 分子式：C₁₈H₂₇NO₂
• 分子量：289.41200
• 相关类别： 原料药 Anesthetic Agents Local anesthetics
• 发布时间：2018-09-12 19:33:34
• 更新时间：2026-07-01 13:22:11

名称

• 中文名: 达克罗宁
• 英文名: dyclonine
• 中文别名: 盐酸达克罗宁; 达克罗宁杂质
• 英文别名: 4'-Butoxy-3-N-piperidino-propiophenon,Dyclon; Dycloninum; 1-Propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl); 4’-butoxy-3-piperidino-propiophenon; Dyclocaine; 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one; Diclonia; Dycloninum [INN-Latin]; Dyclonin; Dyclocainum; Diclonina [INN-Spanish]; 4'-Butoxy-β-piperidinopropiophenone; dyclonin; 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanon; 1-[4-(Butyloxy)phenyl]-3-methoxypropan-1-one; Diclonina; DYCLONINE; Dyclonine [INN:BAN]; 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one; yclonine; 1-(4-butoxy-phenyl)-3-piperidin-1-yl-propan-1-one; Dyclonine HCI; 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone; Dacronine; dyclocaine; DYCLONINE //BP

物化性质

• 密度: 1.017g/cm3
• 沸点: 424.5ºC at 760 mmHg
• 分子式: C₁₈H₂₇NO₂
• 分子量: 289.41200
• 闪点: 210.5ºC
• 精确质量: 289.20400
• PSA: 29.54000
• LogP: 3.86210
• 折射率: 1.517
• 储存条件: 室温，密闭，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UG8672500 CHEMICAL NAME : Propiophenone, 4'-butoxy-3-piperidino- CAS REGISTRY NUMBER : 586-60-7 BEILSTEIN REFERENCE NO. : 0224037 LAST UPDATED : 199709 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C18-H27-N-O2 MOLECULAR WEIGHT : 289.46 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 55 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 60 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 18 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962