942308-58-9

• 常用中文名：(2S,4S)-4-羟基-2-(羟甲基)吡咯烷-1-羧酸苄酯
• 常用英文名：(2S,4S)-BENZYL 4-HYDROXY-2-(HYDROXYMETHYL)PYRROLIDINE-1-CARBOXYLATE
• CAS号：942308-58-9
• 分子式：C₁₂H₁₇NO₂
• 分子量：207.26900
• 发布时间：2018-12-04 06:30:27
• 更新时间：2024-01-10 20:01:03

名称

• 中文名: (2s,4s)-N-cbz-2-羟甲基-4-氧-吡咯烷
• 英文名: (2s,4s)-benzyl-4-hydroxy-2-(hydroxymethyl)pyrrolidine
• 中文别名: (2S,4S)-4-羟基-2-(羟基甲基)-1-吡咯烷羧酸苯基甲酯
• 英文别名: (S)-tert-butyl 1-(benzylamino)-1-oxo-4-methylpentan-2-ylcarbamate; 1-benzyloxycarbamoyl-3-methyl-butyl-carbamic acid tert-butyl ester; (S)-Boc-Leu-NHBn; N-tert-butoxycarbonyl-L-leucine benzylamide; 1-benzyloxycarbonyl-(2S)-hydroxymethyl-(4S)-hydroxypyrrolidine; Carbamic acid,[3-methyl-1-[[(phenylmethyl)amino]carbonyl]butyl]-,1,1-dimethylethyl ester,(R)-(9CI); (2S,4S)-N-Cbz-4-hydroxyprolinol; N-benzyl-N2-(tert-butoxycarbonyl)-L-leucinamide

物化性质

• 密度: 1.298 g/cm3
• 沸点: 433.897ºC at 760 mmHg
• 分子式: C₁₂H₁₇NO₂
• 分子量: 207.26900
• 闪点: 216.214ºC
• 精确质量: 207.12600
• PSA: 43.70000
• LogP: 0.55200
• 折射率: 1.595
• 储存条件: 2-8°C

安全

• 海关编码: 2933990090

合成路线

13504-86-4 ~99% 942308-58-9

文献：Daiichi Sankyo Company, Limited Patent: EP1961750 A1, 2008 ; Location in patent: Page/Page column 108 ;

1365659-16-0 ~55% 942308-58-9

文献：Mereyala, Hari Babu; Pathuri, Gopal; Nagarapu, Lingaiah Synthetic Communications, 2012 , vol. 42, # 9 p. 1278 - 1287

57653-35-7 ~% 942308-58-9

文献：Ceulemans, G.; Aerschot, A. Van; Herdewijn, P. Collection of Czechoslovak Chemical Communications, 1996 , vol. 61, p. S234 - S237

501-53-1 ~% 942308-58-9

文献：Ceulemans, G.; Aerschot, A. Van; Herdewijn, P. Collection of Czechoslovak Chemical Communications, 1996 , vol. 61, p. S234 - S237

618-27-9 ~% 942308-58-9

文献：Ceulemans, G.; Aerschot, A. Van; Herdewijn, P. Collection of Czechoslovak Chemical Communications, 1996 , vol. 61, p. S234 - S237

16217-15-5 ~% 64187-48-0 57653-35-7 942308-58-9

文献：Liu, Yi-Tsung; Wong, Jesse K.; Tao, Meng; Osterman, Rebecca; Sannigrahi, Mousumi; Girijavallabhan, Viyyoor M.; Saksena, Anil Tetrahedron Letters, 2004 , vol. 45, # 32 p. 6097 - 6100

1365659-14-8 ~% 942308-58-9

文献：Mereyala, Hari Babu; Pathuri, Gopal; Nagarapu, Lingaiah Synthetic Communications, 2012 , vol. 42, # 9 p. 1278 - 1287

1365659-15-9 ~% 942308-58-9

文献：Mereyala, Hari Babu; Pathuri, Gopal; Nagarapu, Lingaiah Synthetic Communications, 2012 , vol. 42, # 9 p. 1278 - 1287

上下游产品

上游产品  6
13504-86-4 1365659-16-0 57653-35-7 501-53-1
618-27-9 16217-15-5
下游产品  2
618-27-9 13504-86-4

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%