1256751-11-7

• 常用中文名：波普瑞韦
• 常用英文名：Boceprevir-d9
• CAS号：1256751-11-7
• 分子式：C₂₇H₃₆D₉N₅O₅
• 分子量：528.732
• 发布时间：2018-05-02 08:00:00
• 更新时间：2024-01-13 09:21:53

名称

• 中文名: 波西普韦
• 英文名: (1R,2S,5S)-N-(4-amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]carbamoylamino]-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
• 英文别名: (1R,2S,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide; 3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[[1,1-di(methyl-d)ethyl-2,2,2-d]amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl- , (1R,2S,5S)-; (1R,2S,5S)-N-(4-Amino-1-cyclobutyl-3,4-dioxo-2-butanyl)-6,6-dimethyl-3-(3-methyl-N-{[2-(H)methyl(H)-2-propanyl]carbamoyl}-L-valyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide; [D9]boceprevir; Boceprevir-d9

物化性质

• 密度: 1.2±0.1 g/cm3
• 分子式: C₂₇H₃₆D₉N₅O₅
• 分子量: 528.732
• 精确质量: 528.398560
• PSA: 157.68000
• LogP: 2.05
• 折射率: 1.533

生物活性

描述

合成路线

1373318-85-4 ~86% 1256751-11-7

文献：Ren, Sumei; Royster, Pernilla; Lavey, Carolee; Hesk, David; McNamara, Paul; Koharski, David; Truong, Van; Borges, Scott Journal of Labelled Compounds and Radiopharmaceuticals, 2012 , vol. 55, # 3 p. 108 - 114