13045-94-8

• 常用中文名：Medphalan
• 常用英文名：Medphalan
• CAS号：13045-94-8
• 分子式：C₁₃H₁₈Cl₂N₂O₂
• 分子量：305.20000
• 发布时间：2017-03-31 14:30:52
• 更新时间：2024-01-31 10:30:46

名称

• 英文名: (2R)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
• 英文别名: 4-[Bis-(2-chlor-aethyl)-amino]-D-phenylalanin; (R)-2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoic acid; D-Melphalan; Lopac-M-2011; 4-(bis(2-chloroethyl)amino)-L-phenylalanine; 4-[bis-(2-chloro-ethyl)-amino]-D-phenylalanine; Medphalan; 3026 C. B.; p-Di(2-chloroethyl)amino-d-phenylalanine; MFCD01674289; Melphalan Impurity 12

物化性质

• 密度: 1.32g/cm3
• 沸点: 473.1ºC at 760 mmHg
• 熔点: 182-183ºC (decomp)
• 分子式: C₁₃H₁₈Cl₂N₂O₂
• 分子量: 305.20000
• 闪点: 239.9ºC
• 精确质量: 304.07500
• PSA: 66.56000
• LogP: 2.62530
• 蒸汽压: 9.33E-10mmHg at 25°C
• 折射率: 1.596

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AY3370000 CHEMICAL NAME : Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, D- CAS REGISTRY NUMBER : 13045-94-8 LAST UPDATED : 199510 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C13-H18-Cl2-N2-O2 MOLECULAR WEIGHT : 305.23 WISWESSER LINE NOTATION : QVYZ1R DN2G2G -D HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 113 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 120 mg/kg/9W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors TYPE OF TEST : Specific locus test MUTATION DATA TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 10 mmol/L REFERENCE : JOGNAU Journal of Genetics. (Belghoria, India) V.1-63, 1910-77. Discontinued. Volume(issue)/page/year: 54,146,1956 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 9,167,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 9,167,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

安全

• 海关编码: 2922499990

上下游产品

上游产品  2
297734-00-0 75-21-8
下游产品  0

海关

海关编码	2922499990
中文概述	2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%