145681-01-2

• 常用中文名：1-Boc-2-吡咯烷甲酸甲酯
• 常用英文名：PYRROLIDINE-1,2-DICARBOXYLICACID1-TERT-BUTYLESTER2-METHYLESTER
• CAS号：145681-01-2
• 分子式：C₁₁H₁₉NO₄
• 分子量：229.273
• 发布时间：2018-07-23 13:25:07
• 更新时间：2024-01-14 13:58:26

名称

• 中文名: 1-Boc-2-吡咯烷甲酸甲酯
• 英文名: 1-tert-Butyl 2-methyl pyrrolidine-1,2-dicarboxylate
• 英文别名: 1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester; 1-(tert-Butoxycarbonyl)-2-methylproline; 1-O-tert-butyl 2-O-methyl pyrrolidine-1,2-dicarboxylate; 2-Methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}proline; PYRROLIDINE-1,2-DICARBOXYLICACID1-TERT-BUTYLESTER2-METHYLESTER

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 337.8±35.0 °C at 760 mmHg
• 分子式: C₁₁H₁₉NO₄
• 分子量: 229.273
• 闪点: 158.1±25.9 °C
• 精确质量: 229.131409
• PSA: 55.84000
• LogP: 1.10
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.494
• 储存条件: 室温，干燥

安全

• 海关编码: 2933990090

合成路线

15761-39-4 74-88-4 ~95% 145681-01-2

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BUTTERWORTH, Sam; FINLAY, Maurice, Raymond, Verschoyle; WARD, Richard, Andrew; KADAMBAR, Vasantha, Krishna; CHANDRASHEKAR, Reddy, C.; MURUGAN, Andiappan; REDFEARN, Heather, Marie Patent: WO2013/14448 A1, 2013 ; Location in patent: Page/Page column 103 ; WO 2013/014448 A1

74-88-4 ~95% 145681-01-2

文献：AstraZeneca AB; NPS PHARMACEUTICALS, INC. Patent: US2007/259923 A1, 2007 ; Location in patent: Page/Page column 8 ; US 20070259923 A1

24424-99-5 2133-40-6 ~% 145681-01-2

文献：WO2007/122410 A1, ; Page/Page column 103 ;

24424-99-5 43041-12-9 ~% 145681-01-2

文献：WO2009/146112 A1, ; Page/Page column 40 ; WO 2009/146112 A1

24424-99-5 108645-62-1 ~94% 145681-01-2

文献：Sakaitani, Masahiro; Hori, Keiko; Ohfune, Yasufumi Tetrahedron Letters, 1988 , vol. 29, # 24 p. 2983 - 2984

86953-79-9 79-22-1 ~50% 1243198-88-0 145681-01-2

文献：Organic Letters, , vol. 12, # 18 p. 4176 - 4179

上下游产品

上游产品  8
15761-39-4 74-88-4 24424-99-5 2133-40-6
43041-12-9 108645-62-1 86953-79-9 79-22-1
下游产品  8
59936-29-7 201406-78-2 69610-40-8 15761-39-4
73323-65-6 54503-10-5 317355-80-9 67131-44-6

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%