129-89-5

• 常用中文名：Amizole
• 常用英文名：Amizole
• CAS号：129-89-5
• 分子式：C₁₂H₁₄N₃NaO₄S
• 分子量：319.31200
• 相关类别： 研究领域 其他
• 发布时间：2016-03-04 13:49:55
• 更新时间：2024-01-02 13:41:11
• Sulfamidopyrine (Melaminsulfone) sodium salt是一种活性化合物。 Sulfamidopyrine (sodium salt) 可用于分析研究.

名称

• 英文名: sodium,[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]methanesulfonate
• 英文别名: Sulphamipyrin; Pyrazogin; (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylamino)-methansulfonsaeure,Natriumsalz; (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylamino)-methanesulfonic acid,sodium salt; N-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)aminomethansulfonsaeure natriumsalz; Melaminsulfon; Amizole; SULFAMIPYRINE; 1-Phenyl-2,3-dimethyl-4-amino-5-pyrazolon-N-methanesulfonsaeuren natrium [German]; Amizole (pharmaceutical); Sulfamidopyrin-Natrium; Methanesulfonic acid,(antipyrinylamino)-,monosodium salt

物化性质

• 分子式: C₁₂H₁₄N₃NaO₄S
• 分子量: 319.31200
• 精确质量: 319.06000
• PSA: 104.54000
• LogP: 1.55280
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:6

  4.可旋转化学键数量:4

  5.互变异构体数量:无

  6.拓扑分子极性表面积101

  7.重原子数量:21

  8.表面电荷:0

  9.复杂度:523

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

生物活性

• 描述: Sulfamidopyrine (Melaminsulfone) sodium salt是一种活性化合物。 Sulfamidopyrine (sodium salt) 可用于分析研究.
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Yang, et al. Determination of sulfamipyrine in the presence of analgin by ninhydrin colorimetry. Yiyao Gongye. Issue: 10. Pages: 13-19. Journal. 1984.ISSN: 0255-7223.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : PB1280000 CHEMICAL NAME : Methanesulfonic acid, (antipyrinylamino)-, monosodium salt CAS REGISTRY NUMBER : 129-89-5 LAST UPDATED : 199512 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C12-H15-N3-O4-S.Na MOLECULAR WEIGHT : 320.35 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,213,1955 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - excitement REFERENCE : HDTU** "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933 Volume(issue)/page/year: -,-,1933 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 3500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,213,1955 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 4500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,213,1955

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