71875-81-5

• 常用中文名：反式-4-(马来酰亚胺甲基)环己烷羧酸-NHS
• 常用英文名：Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid-NHS
• CAS号：71875-81-5
• 分子式：C₁₆H₁₈N₂O₆
• 分子量：334.324
• 发布时间：2018-12-02 18:02:55
• 更新时间：2026-08-02 14:24:03

名称

• 中文名: 反式-4-(马来酰亚胺甲基)环己烷羧酸-NHS
• 英文名: 1-[(trans-4-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}cyclohexyl)m ethyl]-1H-pyrrole-2,5-dione
• 中文别名: 反式-2,5-二氧代吡咯烷-1-基4-((2,5-二氧代-2,5-二氢-1H-吡咯-1-基)甲基)环己烷羧酸酯; (1R,4R)-4-(马来酰亚胺甲基)环己烷羧酸琥珀酰亚胺酯; 反式-4-[(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)甲基]环己烷甲酸-2,5-二氧代吡咯烷-1-基酯; 反式-4-马来酰亚胺甲基环己烷羧氮羟基琥珀酸酯
• 英文别名: Trans-4-(Meleimidomethyl)cyclohexancboxylic Acid-NHS; Cyclohexanecboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester, trans; Succinimidyl p-hydroxymethyl benzoate; 2,5-Dioxopyrrolidin-1-yl trans-4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexanecboxylate; trans-2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecboxylate; 2,5-Dioxo-1-pyrrolidinyl trans-4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexanecboxylate; 1-[(4-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione; N-Succinimidyl 4-(N-maleimidomethyl) trans-cyclohexane 1-cboxylate; 2,5-dioxopyrrolidin-1-yl (1r,4r)-4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-cboxylate; 1-[(trans-4-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione; succinimidyl trans-4(maleimidylmethyl)-cyclohexane-1-carboxylate; 2,5-Pyrrolidinedione,1-[[4-(hydroxymethyl)benzoyl]oxy]; 1-[(4-{[(2,5-Dioxopyrrolidin-1-yl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione; (2,5-Dioxopyrrolidin-1-yl) 4-(2,5-dioxopyrrol-1-yl)methylcyclohexanecboxylate; Trans-4-(Maleimidomethyl)cyclohexanecboxylic Acid-NHS; trans-2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl); trans-Cyclohexanecarboxylic Acid 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-,2,5-dioxo-1-pyrrolidinyl ester; trans-2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-cboxylate

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 501.7±42.0 °C at 760 mmHg
• 分子式: C₁₆H₁₈N₂O₆
• 分子量: 334.324
• 闪点: 257.2±27.9 °C
• 精确质量: 334.116486
• PSA: 101.06000
• LogP: -0.39
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.598
• 储存条件: -20°C

安全

• 海关编码: 2925190090

合成路线

6066-82-6 69907-67-1 ~% 71875-81-5

文献：Kimura, Sadaaki; Masunaga, Shin-Ichiro; Harada, Tomohiro; Kawamura, Yasuo; Ueda, Satoshi; Okuda, Kensuke; Nagasawa, Hideko Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 5 p. 1721 - 1728

69907-68-2 5672-89-9 ~89% 71875-81-5

文献：Paterson, Michael J.; Eggleston, Ian M. Synthetic Communications, 2008 , vol. 38, # 2 p. 303 - 308

69907-68-2 6066-82-6 ~% 71875-81-5

文献：Leonard, Nicholas M.; Brunckova, Jarmila Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 9169 - 9174

69907-68-2 6066-82-6 ~% 1337538-64-3 71875-81-5

文献：Leonard, Nicholas M.; Brunckova, Jarmila Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 9169 - 9174

1197-18-8 ~% 71875-81-5

文献：Leonard, Nicholas M.; Brunckova, Jarmila Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 9169 - 9174

108-31-6 6066-82-6 1197-18-8 ~% 71875-81-5

文献：Nielsen; Buchardt Synthesis, 1991 , # 10 p. 819 - 821

上下游产品

上游产品  6
6066-82-6 69907-67-1 69907-68-2 5672-89-9
1197-18-8 108-31-6
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海关

海关编码	2925190090
中文概述	2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%