103995-01-3

• 常用中文名：1-(2,4-二氟苯基)-6,7-二氟-4-氧代-1,4-二氢喹啉-3-甲酸
• 常用英文名：1-(2,4-DIFLUOROPHENYL)-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
• CAS号：103995-01-3
• 分子式：C₁₆H₇F₄NO₃
• 分子量：337.22500
• 发布时间：2017-08-11 21:24:39
• 更新时间：2026-07-12 18:25:52

名称

• 中文名: 1-(2,4-二氟苯基)-6,7-二氟-4-氧代-1,4-二氢喹啉-3-甲酸
• 英文名: 1-(2,4-difluorophenyl)-6,7-difluoro-4-oxoquinoline-3-carboxylic acid
• 英文别名: 1-(2，4-DIFLUORO-PHENYL)-6，7-DIFLUORO-4-OXO-1，4-DIHYDRO-QUINOLINE-3-CBOXYLIC ACID; 1-(2,4-Difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecboxylic Acid; 6,7-difluoro-1-(2,4-difluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-(2,4-Difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxoquinolin-3-cboxylic acid; 3-Quinolinecboxylic acid, 1-(2,4-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo; 1-(2,4-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid; 3-Quinolinecarboxylicacid,1-(2,4-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo; 1-(2,4-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-(2,4-DIFLUOROPHENYL)-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CBOXYLIC ACID; 6,7-difluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid

物化性质

• 密度: 1.618g/cm3
• 沸点: 472.2ºC at 760mmHg
• 分子式: C₁₆H₇F₄NO₃
• 分子量: 337.22500
• 闪点: 239.4ºC
• 精确质量: 337.03600
• PSA: 59.30000
• LogP: 3.24530
• 蒸汽压: 1.02E-09mmHg at 25°C
• 折射率: 1.61

合成路线

108138-17-6 ~10% 103995-01-3

文献：Chu, Daniel T. W.; Nordeen, Carl W.; Hardy, Dwight J.; Swanson, Robert N.; Giardina, William J.; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 168 - 174

446-17-3 ~% 103995-01-3

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

98349-24-7 ~% 103995-01-3

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

108115-67-9 ~% 103995-01-3

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

367-23-7 ~% 103995-01-3

文献：Chu, Daniel T. W.; Nordeen, Carl W.; Hardy, Dwight J.; Swanson, Robert N.; Giardina, William J.; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 168 - 174

88419-56-1 ~% 103995-01-3

文献：Chu, Daniel T. W.; Nordeen, Carl W.; Hardy, Dwight J.; Swanson, Robert N.; Giardina, William J.; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 168 - 174

367-25-9 ~% 103995-01-3

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

129322-83-4 ~% 103995-01-3

文献：Chu, Daniel T. W.; Nordeen, Carl W.; Hardy, Dwight J.; Swanson, Robert N.; Giardina, William J.; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 168 - 174

上下游产品

上游产品  8
108138-17-6 446-17-3 98349-24-7 108115-67-9
367-25-9 367-23-7 88419-56-1 129322-83-4
下游产品  1
108138-27-8