186038-82-4

186038-82-4结构式
186038-82-4结构式

化源商城直购

中文名 (1-氰基-3-甲基丁基)丙二酸二乙酯
英文名 diethyl 2-(1-cyano-3-methylbutyl)propanedioate
中文别名 2-乙氧羰基-3-氰基-5-甲基己酸乙酯
普瑞巴林关键中间体
英文别名 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
QC-8850
2-carboxyethyl-3-cyano-5-methylhexanoic acid ethyl ester
2-carbethoxy-3-cyano-5-methylhexanoic acid ethyl ester
Diethyl (1-cyano-3-methylbutyl)malonate
1-cyano-3-Methylbutyl-Propanedioic acid diethyl ester
Diethyl (1-cyano-3-methylbutyl)malonate
密度 1.044g/cm3
沸点 355.712ºC at 760 mmHg
分子式 C13H21NO4
分子量 255.31000
闪点 155.412ºC
精确质量 255.14700
PSA 76.39000
LogP 1.91468
蒸汽压 0mmHg at 25°C
折射率 1.449

~99%

186038-82-4结构式

186038-82-4

文献:Hu, Shanghui; Martinez, Carlos Alberto; Tao, Junhua; Tully, William Eugene; Kelleher, Patrick; Dumond, Yves Patent: US2005/283023 A1, 2005 ; Location in patent: Page/Page column 18 ;

~96%

186038-82-4结构式

186038-82-4

文献:CADILA HEALTHCARE LIMITED Patent: WO2008/62460 A2, 2008 ; Location in patent: Page/Page column 18-20 ;

~%

186038-82-4结构式

186038-82-4

文献:PFIZER IRELAND PHARMACEUTICALS; DAVIES, Benjamin, Simon; GUZMAN, Mark, M.; MARTINEZ, Carlos, A.; McDAID, Paul, Oliver; O'NEILL, Padraig, Mary; SHANMUGAM, Elango Patent: WO2010/70593 A2, 2010 ; Location in patent: Page/Page column 28-32 ;

~%

186038-82-4结构式

186038-82-4

文献:Wang, Jun; Li, Wei; Liu, Yanling; Chu, Yangyang; Lin, Lili; Liu, Xiaohua; Feng, Xiaoming Organic Letters, 2010 , vol. 12, # 6 p. 1280 - 1283