160857-57-8

• 常用中文名：1-[(4-acetamidophenyl)sulfonylamino]-N-[(E)-(4-methylphenyl)methylideneamino]-3,6-dihydro-2H-pyridine-4-carboxamide
• 常用英文名：1-[(4-acetamidophenyl)sulfonylamino]-N-[(E)-(4-methylphenyl)methylideneamino]-3,6-dihydro-2H-pyridine-4-carboxamide
• CAS号：160857-57-8
• 分子式：C₂₂H₂₅N₅O₄S
• 分子量：455.53000
• 发布时间：2017-04-29 00:40:28
• 更新时间：2025-09-21 10:17:32

名称

• 英文名: 1-[(4-acetamidophenyl)sulfonylamino]-N-[(E)-(4-methylphenyl)methylideneamino]-3,6-dihydro-2H-pyridine-4-carboxamide
• 英文别名: 4-Pyridinecarboxylic acid,1,2,3,6-tetrahydro-1-(((4-(acetylamino)phenyl)sulfonyl)amino)-,((4-methylphenyl)methylene)hydrazide

物化性质

• 密度: 1.326g/cm3
• 分子式: C₂₂H₂₅N₅O₄S
• 分子量: 455.53000
• 精确质量: 455.16300
• PSA: 135.33000
• LogP: 4.82850
• 折射率: 1.638

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : US5908283 CHEMICAL NAME : 4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-1-(((4-(acetylamino)phenyl)sulfony l)amino)-, ((4-methylphenyl)methylene)hydrazide CAS REGISTRY NUMBER : 160857-57-8 LAST UPDATED : 199703 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C22-H25-N5-O4-S MOLECULAR WEIGHT : 455.58 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 44,1029,1994

合成路线

160857-54-5 ~% 160857-57-8

文献：Hanna; Said; Waly Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 9 p. 1029 - 1031

160857-53-4 ~% 160857-57-8

文献：Hanna; Said; Waly Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 9 p. 1029 - 1031

121-60-8 ~% 160857-57-8

文献：Hanna; Said; Waly Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 9 p. 1029 - 1031

104-87-0 160857-55-6 ~% 160857-57-8

文献：Hanna; Said; Waly Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 9 p. 1029 - 1031