21879-81-2

• 常用中文名：Bostrycin
• 常用英文名：Bostrycin
• CAS号：21879-81-2
• 分子式：C₁₆H₁₆O₈
• 分子量：336.29300
• 发布时间：2016-04-01 21:08:43
• 更新时间：2025-08-24 21:13:30
• Bostrycin is an anthraquinone with antibacterial, antiproliferative, and phytotoxic properties. It is active against Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), M. tuberculosis, and C. botulinum. Bostrycin inhibits proliferation of A549 lung adenocarcinoma cells as well as halts the cell cycle at the G0/G1 phase and induces apoptosis in A549 cells. Bostrycin has been used as a cross-linking agent for protein immobilization that retains bacteriostatic activity when immobilized on nonwoven polypropylene fabric.

名称

• 英文名: deoxybostrycin
• 英文别名: (+)-bostrycin; (5R,6R,7S)-5,6,7,9,10-pentahydroxy-2-methoxy-7-methyl-6,8-dihydro-5H-anthracene-1,4-dione

物化性质

• 分子式: C₁₆H₁₆O₈
• 分子量: 336.29300
• 精确质量: 336.08500
• PSA: 144.52000

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CB8068000 CHEMICAL NAME : Anthraquinone, 1,2,3,4-tetrahydro-1-beta,2-beta,3-beta,5,8-pentahydr oxy-6-methoxy-3-methy l- CAS REGISTRY NUMBER : 21879-81-2 LAST UPDATED : 198211 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C16-H16-O8 MOLECULAR WEIGHT : 336.32 WISWESSER LINE NOTATION : L C666 BV IV&&TJ DQ EO1 GQ KQ LQ MQ M1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 3,231,1980