284462-78-8

• 常用中文名：4-(3-氨基苯氧基)-N-甲基-2-吡啶羧胺
• 常用英文名：4-(3-aminophenoxy)-N-methylpyridine-2-carboxamide
• CAS号：284462-78-8
• 分子式：C₁₃H₁₃N₃O₂
• 分子量：243.26100
• 发布时间：2018-12-31 21:58:38
• 更新时间：2026-07-12 17:29:51

名称

• 中文名: 4-(3-氨基苯氧基)-N-甲基-2-吡啶羧胺
• 英文名: 4-(3-aminophenoxy)-N-methylpyridine-2-carboxamide
• 中文别名: 吡非尼酮杂质2; 4-(3-氨基苯氧基)-N-甲基吡啶-2-甲酰胺; 索拉非尼杂质36; 4-(3-氨基苯氧基)-N-甲基吡啶酰胺
• 英文别名: 4-(3-Aminophenoxy)-n-methylpyridine-2-cboxamide; IFLAB-BB F2108-0089; 4-(3-AMINO-PHENOXY)-PYRIDINE-2-CBOXYLIC ACID METHYLAMIDE; 4-(3-aminophenoxy)-N-methyl-pyridine-2-carboxamide; 2-PYRIDINECBOXAMIDE, 4-(3-AMINOPHENOXY)-N-METHYL; 4-(3-amino-phenoxy)-pyridine-2-carboxylic acid methylamide; 4-(3-Aminophenoxy)-N-methylpicolinamide; 4-(3-AMINO-PHENOXY)-N-METHYLPICOLINAMIDE; Pirfenidone Impurity 2; 4-(3-aminophenoxy)-pyridine-2-carbonic acid methyl amide; 3-(-2-(N-methylcarbamoyl)-4-pyridyloxy)aniline; 2-Pyridinecarboxamide,4-(3-aminophenoxy)-N-methyl; 3-(-2-(N-methylcarbamoyl)-pyridin-4-yloxy)aniline; Sorafenib Impurity 36

物化性质

• 密度: 1.241 g/cm3
• 沸点: 472.2ºC at 760 mmHg
• 分子式: C₁₃H₁₃N₃O₂
• 分子量: 243.26100
• 闪点: 239.4ºC
• 精确质量: 243.10100
• PSA: 77.24000
• LogP: 2.78780

合成路线

827029-02-7 ~93% 284462-78-8

文献：MERCK PATENT GMBH Patent: WO2005/5389 A2, 2005 ; Location in patent: Page 171 ; WO 2005/005389 A2

591-27-5 220000-87-3 ~77% 284462-78-8

文献：Yao, Jianwen; He, Zuopeng; Chen, Jing; Sun, Wei; Fang, Hao; Xu, Wenfang Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6549 - 6553,5

98-98-6 ~% 284462-78-8

文献：Yao, Jianwen; He, Zuopeng; Chen, Jing; Sun, Wei; Fang, Hao; Xu, Wenfang Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6549 - 6553,5

24484-93-3 ~% 284462-78-8

文献：Yao, Jianwen; He, Zuopeng; Chen, Jing; Sun, Wei; Fang, Hao; Xu, Wenfang Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6549 - 6553,5

上下游产品

上游产品  5
827029-02-7 591-27-5 220000-87-3 98-98-6
24484-93-3
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