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5116-22-3

5116-22-3结构式
5116-22-3结构式

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中文名 5-甲氧基甲基-2-脱氧尿苷
英文名 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(methoxymethyl)pyrimidine-2,4-dione
英文别名 5-Methoxymethyl-2'-deoxyuridine
Uridine,2'-deoxy-5-methoxymethyl
5-methoxymethyldeoxyuridine
MMUdR
Methoxymethyl deoxyuridine
密度 1.427g/cm3
分子式 C11H16N2O6
分子量 272.25500
精确质量 272.10100
PSA 113.78000
折射率 1.565

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU7900000
CHEMICAL NAME :
Uridine, 2'-deoxy-5-methoxymethyl-
CAS REGISTRY NUMBER :
5116-22-3
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C11-H16-N2-O6
MOLECULAR WEIGHT :
272.29
WISWESSER LINE NOTATION :
T6NVMVJ E1O1 A- ET5OTJ B1Q CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
6 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 gm/kg/15D-I
TOXIC EFFECTS :
Liver - other changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
256 mg/L
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 86,180,1986

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