223131-01-9

• 常用中文名：顺-1-(Boc-氨基)-4-(羟甲基)环己烷
• 常用英文名：tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate
• CAS号：223131-01-9
• 分子式：C₁₂H₂₃NO₃
• 分子量：229.316
• 发布时间：2018-11-17 18:07:50
• 更新时间：2024-01-05 07:14:48

名称

• 中文名: 顺-1-(Boc-氨基)-4-(羟甲基)环己烷
• 英文名: tert-butyl cis-(4-hydroxymethyl)cyclohexylcarbamate
• 中文别名: 顺式-1-(叔丁氧羰氨基)-4-羟基甲基环己烷
• 英文别名: 2-Methyl-2-propanyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate; 2-Methyl-2-propanyl [cis-4-(hydroxymethyl)cyclohexyl]carbamate; Carbamic acid, N-[trans-4-(hydroxymethyl)cyclohexyl]-, 1,1-dimethylethyl ester; Carbamic acid, N-[cis-4-(hydroxymethyl)cyclohexyl]-, 1,1-dimethylethyl ester; tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate; tert-Butyl [cis-4-(hydroxymethyl)cyclohexyl]carbamate

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 351.6±11.0 °C at 760 mmHg
• 分子式: C₁₂H₂₃NO₃
• 分子量: 229.316
• 闪点: 166.4±19.3 °C
• 精确质量: 229.167801
• PSA: 58.56000
• LogP: 1.66
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.485
• 储存条件: 2-8°C，干燥密封

安全

• 海关编码: 2924299090

合成路线

24424-99-5 30134-98-6 ~81% 223131-01-9

文献：Almirall, S.A.; Eastwood, Paul Robert; Bach Taña, Jordi; Pages Santacana, Lluis Miquel Patent: EP2554544 A1, 2013 ; Location in patent: Paragraph 0161 ;

1346527-75-0 ~% 223131-01-9

文献：TAISHO PHARMACEUTICAL CO., LTD.; Arena Pharmaceuticals, Inc Patent: WO2005/95357 A2, 2005 ; Location in patent: Page/Page column 109; 110 ; WO 2005/095357 A2

3685-23-2 ~% 223131-01-9

文献：Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180

62456-15-9 ~% 223131-01-9

文献：Kanuma, Kosuke; Omodera, Katsunori; Nishiguchi, Mariko; Funakoshi, Takeo; Chaki, Shigeyuki; Nagase, Yasuko; Iida, Izumi; Yamaguchi, Jun-ichi; Semple, Graeme; Tran, Thuy-Anh; Sekiguchi, Yoshinori Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 10 p. 3307 - 3319

24424-99-5 ~% 223131-01-9

文献：Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180

53292-90-3 ~% 223131-01-9

文献：Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180

上下游产品

上游产品  5
24424-99-5 30134-98-6 3685-23-2 62456-15-9
53292-90-3
下游产品  2
181308-56-5 509143-00-4

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%