114459-62-0

• 常用中文名：精胺(HBBB)
• 常用英文名：N2,N3,N4-TRIS-(TERT-BUTYLOXYCARBONYL)-1,5,10,14-TETRA-AZA-QUATRODECANE
• CAS号：114459-62-0
• 分子式：C₂₅H₅₀N₄O₆
• 分子量：502.68800
• 发布时间：2016-10-14 08:41:09
• 更新时间：2026-08-02 15:12:04

名称

• 中文名: 精胺(HBBB)
• 英文名: tert-butyl N-(3-aminopropyl)-N-[4-[(2-methylpropan-2-yl)oxycarbonyl-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propyl]amino]butyl]carbamate
• 中文别名: N,N”,N '' - 三(叔丁氧基羰基)精胺; 2-甲基-2-丙基(3-氨基丙基)[4-({[(2-甲基-2-丙基)氧基]羰基}[3-({[(2-甲基-2-丙基)氧基]羰基}氨基)丙基]氨基)丁基]氨基甲酸酯
• 英文别名: tert-butyl (4-((3-aminopropyl)(tert-butoxycbonyl)amino)butyl)(3-((tert-butoxycbonyl)amino)propyl)cbamate; N1,N2,N3-triBOC spermine; Spermine(BBBH); 13-Oxa-2,6,11-triazapentadecanoic acid, 11-(3-aminopropyl)-6-[(1,1-dimethylethoxy)carbonyl]-14,14-dimethyl-12-oxo-, 1,1-dimethylethyl ester; N1,N5,N10-tris boc spermine; 1,5,10-tris-Boc-1,5,10,14-tetraazatetradecane; N,N',N''-Tri(tert-butoxycbonyl)spermine; Spermine(HBBB); N1,N2,N3-tri-Boc-spermine; N2,N3,N4-TRIS-(TERT-BUTYLOXYCBONYL)-1,5,10,14-TETRA-AZA-QUATRODECANE; N1,N5,N10-tri-Boc-spermine; tert-butyl (3-aminopropyl)(4-((tert-butoxycbonyl)(3-((tert-butoxycbonyl)amino)propyl)amino)butyl)cbamate; tri-Boc-spermine; AmbotzSNN1040; N1,N4,N9-tris-Boc-sperMine; N2,N3,N4-Tris-(t-butyloxycbonyl)-1,5,10,14-tetra-aza-quatrodecan; tert-butyl N-(3-aminopropyl)-N-[4-[(2-methylpropan-2-yl)oxycbonyl-[3-[(2-methylpropan-2-yl)oxycbonylamino]propyl]amino]butyl]cbamate; SPERMINE(HBBB); 1,4,9-tris-Boc-1,12-diamino-4,9-diazadodecane; Tris-Boc-Spermine (TLC)

物化性质

• 分子式: C₂₅H₅₀N₄O₆
• 分子量: 502.68800
• 精确质量: 502.37300
• PSA: 123.43000
• LogP: 5.59560

合成路线

71-44-3 24424-99-5 ~46% 114459-62-0

文献：Kim, Jeonghan; Kim, Youngkook; Baek, Kangkyun; Ko, Young Ho; Kim, Dongwoo; Kim, Kimoon Tetrahedron, 2008 , vol. 64, # 36 p. 8389 - 8393

201984-66-9 ~49% 114459-62-0

文献：Zhang, Liuyin; Lee, Hee-Kyoung; Pruess, Timothy H.; White, H. Steve; Bulaj, Grzegorz Journal of Medicinal Chemistry, 2009 , vol. 52, # 6 p. 1514 - 1517

24424-99-5 ~% 114459-62-0

文献：Bueno, G. Jimenez; Klimkait; Gilbert; Simons Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 1 p. 87 - 94

83948-53-2 ~% 114459-62-0

文献：Jasys, V. John; Kelbaugh, Paul B.; Nason, Deane M.; Phillips, Douglas; Rosnack, Kenneth J.; Saccomano, Nicholas A.; Stroh, Justin G.; Volkmann, Robert A. Journal of the American Chemical Society, 1990 , vol. 112, # 18 p. 6696 - 6704

71-44-3 ~% 114459-62-0

文献：Blagbrough, Ian S.; Al-Hadithi, Dima; Geall, Andrew J. Pharmacy and Pharmacology Communications, 1999 , vol. 5, # 3 p. 139 - 144

202145-88-8 ~% 114459-62-0

文献：Blagbrough, Ian S.; Al-Hadithi, Dima; Geall, Andrew J. Pharmacy and Pharmacology Communications, 1999 , vol. 5, # 3 p. 139 - 144

14209-32-6 ~% 114459-62-0

文献：Bueno, G. Jimenez; Klimkait; Gilbert; Simons Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 1 p. 87 - 94

194808-59-8 ~% 114459-62-0

文献：Bueno, G. Jimenez; Klimkait; Gilbert; Simons Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 1 p. 87 - 94

1395276-72-8 ~% 114459-62-0

文献：Corce, Vincent; Morin, Emmanuelle; Guiheneuf, Solene; Renault, Eric; Renaud, Stephanie; Cannie, Isabelle; Tripier, Raphael; Lima, Luis M. P.; Julienne, Karine; Gouin, Sebastien G.; Loreal, Olivier; Deniaud, David; Gaboriau, Francois Bioconjugate Chemistry, 2012 , vol. 23, # 9 p. 1952 - 1968

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71-44-3 24424-99-5 83948-53-2 14209-32-6
194808-59-8 1395276-72-8
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