146725-33-9

• 常用中文名：(1R,2s,3s,5s)-甲基3-(4-氯苯基)-8-氮杂双环[3.2.1]辛烷-2-羧酸
• 常用英文名：(1R,2S,3S,5S)-METHYL 3-(4-CHLOROPHENYL)-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLATE
• CAS号：146725-33-9
• 分子式：C₁₅H₁₈ClNO₂
• 分子量：279.76200
• 发布时间：2019-01-01 10:57:35
• 更新时间：2024-01-09 18:52:29

名称

• 中文名: (1R,2s,3s,5s)-甲基3-(4-氯苯基)-8-氮杂双环[3.2.1]辛烷-2-羧酸
• 英文名: methyl (1S,3S,4S,5R)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate
• 英文别名: des-fluoroethyl-FECNT; (1R,2S,3S,5S)-Methyl 3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate; RTI-110

物化性质

• 分子式: C₁₅H₁₈ClNO₂
• 分子量: 279.76200
• 精确质量: 279.10300
• PSA: 38.33000
• LogP: 3.06590

合成路线

130342-80-2 ~87% 146725-33-9

文献：Zou; Kopajtic; Katz; Wirtz; Justice Jr.; Newman Journal of Medicinal Chemistry, 2001 , vol. 44, # 25 p. 4453 - 4461

873-77-8 ~% 146725-33-9

文献：Goodman; Kung; Kabalka; Switzer Journal of Medicinal Chemistry, 1994 , vol. 37, # 10 p. 1535 - 1542

481-37-8 ~% 146725-33-9

文献：Pijarowska-Kruszyna; Jaron; Kachniarz; Kasprzak; Kowalska; Malkowski; Demphel; Dolle; Mikolajczak Journal of Labelled Compounds and Radiopharmaceuticals, 2014 , vol. 57, # 3 p. 148 - 157

155509-47-0 ~% 146725-33-9

文献：Zeng, Fanxing; Jarkas, Nachwa; Owens, Michael J.; Kilts, Clinton D.; Nemeroff, Charles B.; Goodman, Mark M. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4661 - 4663

484-93-5 ~% 146725-33-9

文献：Pijarowska-Kruszyna; Jaron; Kachniarz; Kasprzak; Kowalska; Malkowski; Demphel; Dolle; Mikolajczak Journal of Labelled Compounds and Radiopharmaceuticals, 2014 , vol. 57, # 3 p. 148 - 157

53-21-4 ~% 146725-33-9

文献：Pijarowska-Kruszyna; Jaron; Kachniarz; Kasprzak; Kowalska; Malkowski; Demphel; Dolle; Mikolajczak Journal of Labelled Compounds and Radiopharmaceuticals, 2014 , vol. 57, # 3 p. 148 - 157

72393-99-8 ~% 146725-33-9

文献：Zou; Kopajtic; Katz; Wirtz; Justice Jr.; Newman Journal of Medicinal Chemistry, 2001 , vol. 44, # 25 p. 4453 - 4461

50-36-2 ~% 146725-33-9

文献：Meltzer, P. C.; Liang, A. Y.; Brownell, A.-L.; Elmaleh, D. R.; Madras, B. K. Journal of Medicinal Chemistry, 1993 , vol. 36, # 7 p. 855 - 862

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