2125-49-7

• 常用中文名：1-(4-甲氧基苯基)-3-二甲氨基-1-丙酮盐酸盐
• 常用英文名：3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride
• CAS号：2125-49-7
• 分子式：C₁₂H₁₈ClNO₂
• 分子量：243.73000
• 发布时间：2018-12-31 18:31:24
• 更新时间：2024-01-09 13:02:40

名称

• 中文名: 1-(4-甲氧基苯基)-3-二甲氨基-1-丙酮盐酸盐
• 英文名: 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride
• 中文别名: 3-(二甲基氨基)-1-(4-甲氧基苯基)-1-丙酮盐酸盐; beta-(二甲基氨基)-4'-甲氧基苯丙酮盐酸盐
• 英文别名: 3-dimethylamino-1-(4-methoxyphenyl)-1-propanone hydrochloride; 3-(DIMETHYLAMINO)-4'-METHOXYPROPIOPHENONE HYDROCHLORIDE; beta-(Dimethylamino)-4'-methoxypropiophenone hydrochloride

物化性质

• 密度: 1.027g/cm3
• 沸点: 318.2ºC at 760 mmHg
• 熔点: 184-186 ºC (ethanol acetone )
• 分子式: C₁₂H₁₈ClNO₂
• 分子量: 243.73000
• 闪点: 146.2ºC
• 精确质量: 243.10300
• PSA: 29.54000
• LogP: 2.63160
• 蒸汽压: 0.000368mmHg at 25°C
• 折射率: 1.512
• 储存条件: 室温，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UH0730000 CHEMICAL NAME : Propiophenone, 3-(dimethylamino)-4'-methoxy-, hydrochloride CAS REGISTRY NUMBER : 2125-49-7 LAST UPDATED : 199203 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C12-H17-N-O2.Cl-H MOLECULAR WEIGHT : 243.76 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 25,437,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 275 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,994,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 258 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 24,833,1990

安全

• 海关编码: 2923900090

合成路线

30354-18-8 100-06-1 ~13% 2125-49-7

文献：Dimmock, Jonathan R.; Patil, Shirish A.; Leek, Donald M.; Warrington, Robert C.; Fang, Wei D. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 545 - 552

50-00-0 124-40-3 100-06-1 ~% 2125-49-7

文献：Heterocyclic Communications, , vol. 11, # 2 p. 135 - 138

50-00-0 506-59-2 100-06-1 ~58% 2125-49-7

文献：Brahmbhatt; Pandya Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 5 p. 419 - 421

上下游产品

上游产品  5
50-00-0 506-59-2 100-06-1 30354-18-8
124-40-3
下游产品  10
108664-74-0 104941-13-1 2004-63-9 121-97-1
17159-98-7 7448-86-4 88384-31-0 78993-93-8
78993-94-9 78993-95-0

海关

海关编码	2923900090
中文概述	2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%