119945-59-4

• 常用中文名：(R)-(+)-非洛地平
• 常用英文名：(R)-Felodipine
• CAS号：119945-59-4
• 分子式：C₁₈H₁₉Cl₂NO₄
• 分子量：384.25400
• 发布时间：2017-02-21 00:39:05
• 更新时间：2026-08-21 19:05:52

名称

• 中文名: (R)-(+)-非洛地平
• 英文名: 5-O-ethyl 3-O-methyl (4S)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• 中文别名: 乙基甲基4-(2,3-二氯苯基)-2,6-二甲基-1,4-二氢-3,5-吡啶二羧酸酯; R-(+)-非洛地平; 5-甲基(R)-4-(2,3-二氯苯基)-2,6-二甲基-1,4-二氢吡啶-3,5-二甲酸3-乙酯
• 英文别名: 3,5-Pyridinedicboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester, (4R); (4R)-4α-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicboxylic acid 3-ethyl 5-methyl ester; (4R)-4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicboxylic Acid 3-Ethyl 5-Methyl Ester; Bio-0040; 3,5-Pyridinedicboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester, (4R); 3-Ethyl 5-methyl (R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicboxylate; 3,5-Pyridinedicboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester, (R); 5-O-ethyl 3-O-methyl (4S)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicboxylate

物化性质

• 分子式: C₁₈H₁₉Cl₂NO₄
• 分子量: 384.25400
• 精确质量: 383.06900
• PSA: 64.63000
• LogP: 4.29310

合成路线

127634-12-2 ~% 119945-59-4

文献：Tetrahedron Letters, , vol. 30, # 46 p. 6423 - 6426

127634-14-4 74-88-4 ~% 119945-59-4

文献：Tetrahedron Letters, , vol. 30, # 46 p. 6423 - 6426

72509-76-3 ~% 119945-59-4 105618-03-9

文献：Helvetica Chimica Acta, , vol. 83, # 4 p. 767 - 776

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