117718-82-8

• 常用中文名：3-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine
• 常用英文名：3-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine
• CAS号：117718-82-8
• 分子式：C₇H₇BrN₄
• 分子量：227.06100
• 发布时间：2018-06-21 16:39:12
• 更新时间：2024-01-10 18:12:30

名称

• 英文名: 3-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine

物化性质

• 密度: 1.81g/cm3
• 分子式: C₇H₇BrN₄
• 分子量: 227.06100
• 精确质量: 225.98500
• PSA: 42.22000
• LogP: 1.60650
• 折射率: 1.737

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NJ5097590 CHEMICAL NAME : Imidazo(1,2-a)pyrazin-8-amine, 3-bromo-N-methyl- CAS REGISTRY NUMBER : 117718-82-8 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C7-H7-Br-N4 MOLECULAR WEIGHT : 227.09 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 954 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 35,3353,1992

安全

• 海关编码: 2933990090

合成路线

936361-36-3 74-89-5 ~49% 117718-82-8

文献：Sugen, Inc. Patent: US2004/220189 A1, 2004 ; Location in patent: Page 22 ; US 20040220189 A1

274-79-3 ~% 117718-82-8

文献：Bonnet, Pierre A.; Michel, Alain; Laurent, Florence; Sablayrolles, Claire; Rechencq, Eliane; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 18 p. 3353 - 3358

63744-21-8 74-89-5 ~% 117718-82-8

文献：Bonnet, Pierre A.; Michel, Alain; Laurent, Florence; Sablayrolles, Claire; Rechencq, Eliane; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 18 p. 3353 - 3358

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%