34580-65-9

• 常用中文名：[[1-[3-(Trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy]acetic acid ethyl ester
• 常用英文名：[[1-[3-(Trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy]acetic acid ethyl ester
• CAS号：34580-65-9
• 分子式：C₁₇H₁₄F₃N₃O₃
• 分子量：365.30700
• 发布时间：2017-03-01 05:38:34
• 更新时间：2024-02-26 17:45:49

名称

• 英文名: ethyl 2-[1-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-b]pyridin-3-yl]oxyacetate
• 英文别名: itf 1030

物化性质

• 分子式: C₁₇H₁₄F₃N₃O₃
• 分子量: 365.30700
• 精确质量: 365.09900
• PSA: 66.24000
• LogP: 3.38120

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AK0403000 CHEMICAL NAME : Acetic acid, ((1-(alpha,alpha,alpha-trifluoro-m-tolyl)-1H-pyrazolo (3,4-b)pyridin-3-yl)o xy)-, ethyl ester CAS REGISTRY NUMBER : 34580-65-9 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C17-H14-F3-N3-O3 MOLECULAR WEIGHT : 365.34 WISWESSER LINE NOTATION : T56 BNN INJ BR CXFFF& DO1VO2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 810 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972