75852-54-9

• 常用中文名：3-氟联苯-5-乙酸
• 常用英文名：5-Fluoro-3-biphenylacetic acid
• CAS号：75852-54-9
• 分子式：C₁₄H₁₁FO₂
• 分子量：230.23400
• 发布时间：2018-09-27 20:18:42
• 更新时间：2024-01-09 20:19:15

名称

• 中文名: 3-氟联苯-5-乙酸
• 英文名: 2-(3-fluoro-5-phenylphenyl)acetic acid
• 英文别名: 5-fluoro-3-biphenylylacetic acid; 5-Fluoro-3-biphenylacetic acid; 2-(5-Fluoro-[1,1'-biphenyl]-3-yl)acetic acid; 3-BIPHENYLACETIC ACID,5-FLUORO

物化性质

• 密度: 1.235g/cm3
• 沸点: 379.5ºC at 760 mmHg
• 分子式: C₁₄H₁₁FO₂
• 分子量: 230.23400
• 闪点: 183.3ºC
• 精确质量: 230.07400
• PSA: 37.30000
• LogP: 3.11980
• 折射率: 1.579

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DU8333000 CHEMICAL NAME : 3-Biphenylacetic acid, 5-fluoro- CAS REGISTRY NUMBER : 75852-54-9 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C14-H11-F-O2 MOLECULAR WEIGHT : 230.25 WISWESSER LINE NOTATION : QV1R CF ER HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 566 mg/kg TOXIC EFFECTS : Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,43,1981

合成路线

75852-33-4 ~88% 75852-54-9

文献：Tamura, Yasumitsu; Yoshimoto, Yoshihiko; Kunimoto, Katsutoshi; Tada, Shin-ichi; Matsumura, Shingo; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 43 - 47

75852-22-1 ~% 75852-54-9

文献：Tamura, Yasumitsu; Yoshimoto, Yoshihiko; Kunimoto, Katsutoshi; Tada, Shin-ichi; Matsumura, Shingo; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 43 - 47