150986-62-2

• 常用中文名：(3R,4R)-3,4-二羟基吡咯烷-1-羧酸叔丁酯
• 常用英文名：tert-butyl (3R,4R)-3,4-dihydroxypyrrolidine-1-carboxylate
• CAS号：150986-62-2
• 分子式：C₉H₁₇NO₄
• 分子量：203.236
• 发布时间：2016-03-05 01:28:27
• 更新时间：2024-01-12 19:55:34

名称

• 中文名: (3R,4R)-3,4-二羟基吡咯烷-1-羧酸叔丁酯
• 英文名: tert-butyl (3R,4R)-3,4-dihydroxypyrrolidine-1-carboxylate
• 英文别名: 2-Methyl-2-propanyl (3S,4S)-3,4-dihydroxy-1-pyrrolidinecarboxylate; tert-butyl S,S-3,4-dihydroxypyrrolidine-1-carboxylate; 1-Pyrrolidinecarboxylic acid, 3,4-dihydroxy-, 1,1-dimethylethyl ester, (3S,4S)-; S,S-3,4-dihydroxypyrrolidine-1-carboxylic acid tert-butyl ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 300.6±42.0 °C at 760 mmHg
• 分子式: C₉H₁₇NO₄
• 分子量: 203.236
• 闪点: 135.6±27.9 °C
• 精确质量: 203.115753
• PSA: 70.00000
• LogP: -0.79
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.534
• 储存条件: 室温

合成路线

24424-99-5 90481-32-6 ~83% 150986-62-2

文献：Nagel, Ulrich Angewandte Chemie, 1984 , vol. 96, # 6 p. 425 - 426

24424-99-5 90365-74-5 ~93% 150986-62-2

文献：Marradi, Marco; Cicchi, Stefano; Sansone, Francesco; Casnati, Alessandro; Goti, Andrea Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 951 - 957

1428671-12-8 ~% 150986-62-2

文献：Guerreiro, Luis R.; Carreiro, Elisabete P.; Fernandes, Luis; Cardote, Teresa A.F.; Moreira, Rui; Caldeira, Ana T.; Guedes, Rita C.; Burke Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1911 - 1917

762-75-4 90481-32-6 ~55% 150986-62-2

文献：ARRAY BIOPHARMA INC.; BLAKE, James, F; DELISLE, Robert, Kirk; DE MEESE, Lisa, A.; GRAHAM, James, M.; LE HUEROU, Yvan; LYON, Michael; ROBINSON, John, E.; WALLACE, Eli, M.; WANG, Bin; XU, Rui Patent: WO2012/154274 A1, 2012 ; Location in patent: Page/Page column 148 ; WO 2012/154274 A1

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