52749-50-5

• 常用中文名：8-羟基-3,4-二氢-2(1H)-喹啉酮
• 常用英文名：8-HYDROXY-3,4-DIHYDRO-2-QUINOLINONE
• CAS号：52749-50-5
• 分子式：C₉H₉NO₂
• 分子量：163.173
• 发布时间：2018-12-25 15:55:22
• 更新时间：2026-07-05 17:22:01

名称

• 中文名: 8-羟基-3,4-二氢-2-喹啉酮
• 英文名: 8-hydroxy-3,4-dihydro-1H-quinolin-2-one
• 中文别名: 阿立哌唑杂质; 8-羟基-3,4-二氢喹啉-2(1H)-酮; 8-羟基-3,4-二氢-2-喹啉; 阿立哌唑杂质5; 依匹哌唑杂质71
• 英文别名: ipiprazole Impurity 5; ipiprazole impurities1789; 8-hydroxy-1,2,3,4-tetrahydroquinolin-2-one; 8-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline; ipiprazole Impurity:3,4-Dihydro-8-hydroxyquinolin-2(1H)-one; 3,4-Dihydro-8-hydroxy-2(1H)-quinolinone; ipiprazoleImpurityA; 2(1H)-Quinolinone, 3,4-dihydro-8-hydroxy; 8-Hydroxy-3,4-dihydroquinolin-2(1H); 8-Hydroxy-3,4-dihydrocbostyril; N1-(2-chloroethyl)-N2-(2,3-dichlorophenyl)ethane-1,2-diamine; 8-Hydroxy-2(1H)-3,4-dihydroquinolinone; Brexpiprazole Impurity 71; 8-Hydroxy-3,4-dihydroquinolin-2(1H)-one; 8-Hydroxy-3,4-dihydrocarbostyril; 8-Hydroxy-3,4-dihydro-2(1H)-quinolinone; 8-hydroxy-3,4-dihydroquinolin-2(1H)-one; 8-Hydroxy-3,4-dihydro-2-quinolinone; Brexpiprazole Dimer Impurity 15

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 381.9±42.0 °C at 760 mmHg
• 分子式: C₉H₉NO₂
• 分子量: 163.173
• 闪点: 184.8±27.9 °C
• 精确质量: 163.063324
• PSA: 49.33000
• LogP: 0.98
• 外观性状: 淡黄色晶体或粉末
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.604
• 储存条件: 室温

安全

• 海关编码: 2933790090

合成路线

19343-16-9 ~48% 52749-50-5

文献：ASTRAZENECA AB Patent: WO2005/54249 A1, 2005 ; Location in patent: Page/Page column 21 ; WO 2005/054249 A1

15450-76-7 ~% 52749-50-5

文献：Cavallito; Haskell Journal of the American Chemical Society, 1944 , vol. 66, p. 1166,1168

55860-23-6 ~% 52749-50-5

文献：Pai; Samel Asian Journal of Chemistry, 2011 , vol. 23, # 4 p. 1655 - 1660

90-04-0 ~% 52749-50-5

文献：Pai; Samel Asian Journal of Chemistry, 2011 , vol. 23, # 4 p. 1655 - 1660

53899-19-7 ~% 52749-50-5

文献：Sidhu et al. Justus Liebigs Annalen der Chemie, 1959 , vol. 627, p. 224,225

105910-09-6 ~% 52749-50-5

文献：Sidhu et al. Justus Liebigs Annalen der Chemie, 1959 , vol. 627, p. 224,225

上下游产品

上游产品  6
19343-16-9 15450-76-7 55860-23-6 90-04-0
53899-19-7 105910-09-6
下游产品  1
53899-19-7

海关

海关编码	2933790090
中文概述	2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%