14056-64-5

• 常用中文名：10H-Phenothiazine-10-propanamine,N,N,b-trimethyl-2-(methylthio)-,hydrochloride (1:1)
• 常用英文名：10H-Phenothiazine-10-propanamine,N,N,b-trimethyl-2-(methylthio)-,hydrochloride (1:1)
• CAS号：14056-64-5
• 分子式：C₁₉H₂₅ClN₂S₂
• 分子量：380.99800
• 发布时间：2016-11-17 17:49:36
• 更新时间：2024-01-02 19:38:09

名称

• 英文名: N,N,2-trimethyl-3-(2-methylsulfanylphenothiazin-10-yl)propan-1-amine,hydrochloride
• 英文别名: Promethazine sulfoxide; 10-(2-dimethyl-aminopropyl)-phenothiazine sulphoxide; dimethyl-[2-methyl-3-(2-methylsulfanyl-phenothiazin-10-yl)-propyl]-amine,monohydrochloride; Methiomeprazin*HCl; Romergan sulfoxide; Promethazine 5-Oxide; 10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide; Promethiazine sulfoxide; Promethazine 5-Sulfoxide; promethasine sulfoxide; methiomeprazine,monohydrochloride

物化性质

• 沸点: 480.8ºC at 760 mmHg
• 分子式: C₁₉H₂₅ClN₂S₂
• 分子量: 380.99800
• 闪点: 244.6ºC
• 精确质量: 380.11500
• PSA: 57.08000
• LogP: 6.07590
• 蒸汽压: 2.1E-09mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SO6300000 CHEMICAL NAME : Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-(methylthio)- , hydrochloride CAS REGISTRY NUMBER : 14056-64-5 LAST UPDATED : 199012 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C19-H24-N2-S2.Cl-H MOLECULAR WEIGHT : 381.03 WISWESSER LINE NOTATION : T C666 BN ISJ B1Y1&1N1&1 ES1 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 145 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972