53-31-6

• 常用中文名：美地巴嗪
• 常用英文名：1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine
• CAS号：53-31-6
• 分子式：C₂₅H₂₆N₂O₂
• 分子量：386.48600
• 发布时间：2018-02-25 08:00:00
• 更新时间：2024-02-23 21:08:05

名称

• 中文名: 美地巴嗪
• 英文名: 1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine
• 英文别名: Medibazine [INN:DCF]; Medibazina [DCIT]; 1-benzhydryl-4-benzo[1,3]dioxol-5-ylmethyl-piperazine; Benzhydryl-1-piperonyl piperazine; Medibazine; Piperazine,1-diphenylmethyl-4-piperonyl; EINECS 200-168-7; Medibazinum [INN-Latin]; Vialibran; 1-(Diphenylmethyl)-4-piperonylpiperazine

物化性质

• 密度: 1.207g/cm3
• 沸点: 503.2ºC at 760mmHg
• 分子式: C₂₅H₂₆N₂O₂
• 分子量: 386.48600
• 闪点: 139.9ºC
• 精确质量: 386.19900
• PSA: 24.94000
• LogP: 4.19830
• 折射率: 1.633

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL6650000 CHEMICAL NAME : Piperazine, 1-diphenylmethyl-4-piperonyl- CAS REGISTRY NUMBER : 53-31-6 BEILSTEIN REFERENCE NO. : 0901009 LAST UPDATED : 199709 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C25-H26-N2-O2 MOLECULAR WEIGHT : 386.53 WISWESSER LINE NOTATION : T56 BO DO CHJ C1- AT6N DNTJ DYR&R HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 41 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 151,313,1964

安全

• 海关编码: 2934999090

合成路线

78358-16-4 841-77-0 ~% 53-31-6

文献：Bhandare, Richie R.; Canney, Daniel J. Medicinal Chemistry, 2014 , vol. 10, # 4 p. 361 - 375

495-76-1 ~% 53-31-6

文献：Bhandare, Richie R.; Canney, Daniel J. Medicinal Chemistry, 2014 , vol. 10, # 4 p. 361 - 375

上下游产品

上游产品  3
78358-16-4 841-77-0 495-76-1
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海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%