6677-99-2

• 常用中文名：氢化可的松 21-丁酸盐
• 常用英文名：Hydrocortisone 21-Butyrate
• CAS号：6677-99-2
• 分子式：C₂₅H₃₆O₆
• 分子量：432.55000
• 发布时间：2018-06-30 11:14:24
• 更新时间：2026-07-24 10:15:12

名称

• 中文名: 氢化可的松 21-丁酸盐
• 英文名: Hydrocortisone 21-Butyrate
• 中文别名: 21-丁酸氢化可的松 标准品; 氢化可的松21-丁酸酯; 21-丁酸氢化可的松; 醋酸氢化可的松杂质45; 醋酸氢化可的松杂质8
• 英文别名: Hydrocortisone Acetate Impurity 8; (11β)-11,17-Dihydroxy-21-(1-oxobutoxy)pregn-4-ene-3,20-dione; hydrocortisone-21-butyrate; cortisol 21-butyrate; 11β,17-Dihydroxy-21-(1-oxobutoxy)pregn-4-ene-3,20-dione; HB21; hydrocortisone butyrate; 11beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-butyrate; Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(1-oxobutoxy)-, (11β); Hydrocortisone Acetate Impurity 45

物化性质

• 密度: 1.23g/cm3
• 沸点: 594.8ºC at 760 mmHg
• 熔点: 191-193ºC
• 分子式: C₂₅H₃₆O₆
• 分子量: 432.55000
• 闪点: 197.7ºC
• 精确质量: 432.25100
• PSA: 100.90000
• LogP: 3.13260
• 折射率: 1.564

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GM9002500 CHEMICAL NAME : Cortisol, 21-butyrate CAS REGISTRY NUMBER : 6677-99-2 LAST UPDATED : 198610 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C25-H36-O6 MOLECULAR WEIGHT : 432.61 WISWESSER LINE NOTATION : L E5 B666 OV MUTJ A1 CQ E1 FV1OV3 FQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2070 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 6(Suppl 1),1,1981

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