170123-25-8

• 常用中文名：N-Boc-3-氧代吡咯烷-2-甲酸乙酯
• 常用英文名：Ethyl N-Boc-3-oxopyrrolidine-2-carboxylate
• CAS号：170123-25-8
• 分子式：C₁₂H₁₉NO₅
• 分子量：257.283
• 发布时间：2019-01-10 13:21:55
• 更新时间：2026-08-14 17:21:08

名称

• 中文名: n-boc-3-氧代吡咯烷-2-羧酸乙酯
• 英文名: 3-Oxo-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester
• 中文别名: 1-N-BOC-3-氧代-吡咯烷-2-甲酸乙酯; 1-叔丁基2-乙基3-氧吡咯烷-,2-二羧酸酯; N-BOC-3-氧代吡咯烷-2-羧酸乙酯; 1-叔丁氧羰基-3-氧代吡咯烷-2-甲酸乙酯; 乙基N-BOC-3-氧代吡咯烷-2-羧酸盐; 1-叔丁基2-乙基3-氧代吡咯烷-1,2-二羧酸酯; N-BOC-3-氧代吡咯烷-2-甲酸乙酯
• 英文别名: 3-(1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)propanoic acid; 1-tert-butyl 2-ethyl 3-oxopyrrolidine-1,2-dicarboxylate; 3-(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)propanoic acid; N-Boc-3-Oxopyrrolidine-2-cboxylic acid ethyl ester; 2-Ethyl 1-(2-methyl-2-propanyl) 3-oxo-1,2-pyrrolidinedicarboxylate; 3-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)propanoic acid; 1,2-Pyrrolidinedicarboxylic acid, 3-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester; 1,2-Pyrrolidinedicboxylic acid, 3-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester; 3-oxo-1,2-benzisothiazoline-2-propionic acid 1,1-dioxide; O1-tert-butyl O2-ethyl 3-oxopyrrolidine-1,2-dicboxylate; Ethyl 1-(tert-butoxycbonyl)pyrrolidin-3-one-2-cboxylate; 1-tert-Butyl 2-ethyl 3-oxopyrrolidine-1,2-dicboxylate; N-Boc-3-oxopyrrolidine-2-cboxylate; Ethyl N-Boc-3-oxopyrrolidine-2-cboxylate; 3-oxo-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl)-2-ethyl ester; 1-(tert-Butoxycbonyl)pyrrolidin-3-one-2-cboxylic acid ethyl ester; Ethyl 1-(tert-butoxycarbonyl)-3-oxopyrrolidine-2-carboxylate; N-tert-butyloxycarbonyl-3-keto-DL-proline ethyl ester; (R/S)-1-tert-butyl 2-ethyl 3-oxopyrrolidine-1,2-dicarboxylate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 348.0±42.0 °C at 760 mmHg
• 分子式: C₁₂H₁₉NO₅
• 分子量: 257.283
• 闪点: 164.3±27.9 °C
• 精确质量: 257.126312
• PSA: 72.91000
• LogP: 0.76
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.487
• 储存条件: 室温，干燥

安全

• 海关编码: 2933990090

合成路线

146256-97-5 ~76% 170123-25-8

文献：Knight, David W.; Sibley, A. William Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 15 p. 2179 - 2187

1268159-53-0 ~98% 170123-25-8

文献：Hovey, M. Todd; Eklund, Emily J.; Pike, Robert D.; Mainkar, Anshul A.; Scheerer, Jonathan R. Organic Letters, 2011 , vol. 13, # 5 p. 1246 - 1249

170123-28-1 ~73% 170123-25-8

文献：Pellegrini, Nadia; Schmitt, Martine; Guery, Sebastien; Bourguignon, Jean-Jacques Tetrahedron Letters, 2002 , vol. 43, # 17 p. 3243 - 3246

3783-61-7 ~% 170123-25-8

文献：Calugi, Chiara; Trabocchi, Andrea; Lalli, Claudia; Guarna, Antonio European Journal of Medicinal Chemistry, 2012 , vol. 56, p. 96 - 107

24424-99-5 ~% 170123-25-8

文献：Cooper, Jeremy; Gallagher, Peter T.; Knight, David W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 12 p. 1313 - 1318

146256-97-5 ~46% 146256-98-6 170123-25-8

文献：Cooper, Jeremy; Gallagher, Peter T.; Knight, David W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 12 p. 1313 - 1318

1140510-99-1 ~% 170123-25-8

文献：Hovey, M. Todd; Eklund, Emily J.; Pike, Robert D.; Mainkar, Anshul A.; Scheerer, Jonathan R. Organic Letters, 2011 , vol. 13, # 5 p. 1246 - 1249

上下游产品

上游产品  4
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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%