133438-58-1

• 常用中文名：JWH-193
• 常用英文名：JWH-193
• CAS号：133438-58-1
• 分子式：C₂₆H₂₆N₂O₂
• 分子量：398.497
• 发布时间：2016-04-23 09:45:15
• 更新时间：2024-01-14 12:50:42
• JWH 193 is a synthetic cannabinoid (CB) which binds the central CB1 receptor with high affinity (Ki = 6 nM). This aminoalkylindole shares structural features with the antinociceptive CB1 agonists pravadoline and WIN 55,212-2.1 The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.

名称

• 英文名: (4-methylnaphthalen-1-yl)-[1-(2-morpholin-4-ylethyl)indol-3-yl]methanone
• 英文别名: (4-methylnaphthalen-1-yl){1-[2-(morpholin-4-yl)ethyl]-1H-indol-3-yl}methanone; Methanone, (4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]-; (4-Methyl-1-naphthyl){1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl}methanone; JWH-193

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 623.9±50.0 °C at 760 mmHg
• 分子式: C₂₆H₂₆N₂O₂
• 分子量: 398.497
• 闪点: 331.1±30.1 °C
• 精确质量: 398.199432
• PSA: 34.47000
• LogP: 4.80
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.638

合成路线

87700-67-2 72395-48-3 ~% 133438-58-1

文献：Huffman, John W.; Mabon, Ross; Wu, Ming-Jung; Lu, Jianzhong; Hart, Richard; Hurst, Dow P.; Reggio, Patricia H.; Wiley, Jenny L.; Martin, Billy R. Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 4 p. 539 - 549

4488-40-8 ~% 133438-58-1

文献：Eissenstat, Michael A.; Bell, Malcolm R.; D'Ambra, Thomas E.; Alexander, E. John; Daum, Sol J.; et al. Journal of Medicinal Chemistry, 1995 , vol. 38, # 16 p. 3094 - 3105

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