129332-29-2

• 常用中文名：氟伐二醇
• 常用英文名：(3R,5S)-Fluvastatin tert-Butyl Ester
• CAS号：129332-29-2
• 分子式：C₂₈H₃₄FNO₄
• 分子量：467.572
• 相关类别： 原料药 循环系统用药 抗动脉粥样硬化药
• 发布时间：2018-02-12 08:00:00
• 更新时间：2026-07-11 12:30:34

名称

• 中文名: 氟伐二醇
• 英文名: tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate
• 中文别名: 氟伐他汀钠杂质B 标准品; 氟伐他汀钠相关物质B 标准品; 氟伐二醇 (氟伐他汀钠); 消旋氟伐他汀钠杂质B; 3 F-4(E)-7-[3-(4-氟苯基)-1-异丙基吲哚-2-基]-3,5-二羟基-6-庚烯酸叔丁酯; (E)-7-[3'-(4''-氟苯基)-1'-异丙基吲哚-2'-基]-3,5-二羟基-6-庚烯酸叔丁酯(氟伐他汀杂质); (E)-7-[3'-(4''-氟苯基)-1'-异丙基吲哚-2'-基]-3,5-二羟基-6-庚烯酸叔丁酯; 氟伐他汀相关化合物B; 氟伐他汀相关物质B3; 氟伐他汀相关物质B; F-4(E)-7-[3-(4-氟苯基)-1-异丙基吲哚-2-基]-3,5-二羟基-6-庚烯酸叔丁酯; 氟伐他汀钠中间体 F4
• 英文别名: tert-Butyl Fluvastatin; Fluvastatin Related Compound B; tert-butyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate; tert-Butyl (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxy-6-htenoate; Fluvastatin Related Compound B ([R*,S*-E]-(+/-)-7-[3-(4-fluorophenyl)-1-methylethyl-1H-indol-2-yl]; Fluvastatin sodiuM interMediate F4; (6E)-7-{3-[1-(4-fluorophenyl)propan-2-yl]-1H-indol-2-yl}-3,5-dihydroxy-8,8-diMethylnon-6-enoate; Fluvastatin Related CoMpound B; Fluvastatin Impurity B (as Racemate); tert-Butyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate; 1,1-Dimethylethyl (3RS,5SR,6E)-7-[3; Fluvastatin Sodium Impurity B as Racemate; 7-[3-(4-fluorophenyl)-1-propan-2-yl-2-indolyl]-3,5-dihydroxy-6-htenoic acid tert-butyl ester; t-Butyl(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate; tert-Butyl (E)-3,5-d; t-Butyl(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6; t-Butyl(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-htenoate; Fluvastatin Related Compound; tert-Butyl(R*,S*-(E))-(±)-7-[3-(4-fluorophenyl)-1-(-1-Methylethyl) -1H-indol-2-yl]-3,5-dihydroxyht-6-enoate; Tert-butyl (3R,5S,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyht-6-enoate; tert-Butyl rel-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyht-6-enoate; Fluvastatin Related Compound B (15 mg) ([R*,S*-E]-(+/-)-7-[3-(4-fluorophenyl)-1-methylethyl-1H-indol-2-yl]-3,5-dihydroxy-6-htenoic acid 1,1, dimethylethyl ester); tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-htenoate; (3S,5R,E)-tert-butyl 7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyht-6-enoate (Fluvastatin Impurity）; 2-Methyl-2-propanyl (6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate; 2-Methyl-2-propanyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate; tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-htenoate //BP; 6-Htenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-rel; tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-htenoate (Fluvastatin sodium salt); t-Butyl(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methyle; Fluvastatin RC B; tert-Butyl Fluvastatin //BP; 1,1-Dimethylethyl (3RS,5SR,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyh; tert-Butyl (6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate; (R*,S*-(E))-(±)-7-[3- (4-fluorophenyl)-1-(-1-Methylethyl)-1H-indol-2-yl]-3, 5-dihydroxy-6-htenoic acid 1,1-diMethyl ester; ert-Butyl(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-htenoate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 642.3±55.0 °C at 760 mmHg
• 分子式: C₂₈H₃₄FNO₄
• 分子量: 467.572
• 闪点: 342.2±31.5 °C
• 精确质量: 467.247192
• PSA: 71.69000
• LogP: 5.44
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.553

安全

• 危险品运输编码: NONH for all modes of transport