146464-93-9

• 常用中文名：4-[1-[(2,4-二氨基-6-蝶啶基)甲基]-3-丁炔基]苯甲酸
• 常用英文名：4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoicacid
• CAS号：146464-93-9
• 分子式：C₁₈H₁₆N₆O₂
• 分子量：348.35900
• 发布时间：2017-10-22 14:25:12
• 更新时间：2025-09-14 12:23:18

名称

• 中文名: 4-[1-[(2,4-二氨基-6-蝶啶基)甲基]-3-丁炔基]苯甲酸
• 英文名: 4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoic acid
• 英文别名: S14-2815; QC-6152; 10-propargyl-4-deoxy-4-amino-10-deazapteroic acid; 4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic acid

物化性质

• 分子式: C₁₈H₁₆N₆O₂
• 分子量: 348.35900
• 精确质量: 348.13300
• PSA: 141.63000
• LogP: 2.14330
• 储存条件: 2-8°C

合成路线

146464-92-8 ~59% 146464-93-9

文献：Vaidya, Chitra M.; Wright, Joel E.; Rosowsky, Andre Journal of Medicinal Chemistry, 2002 , vol. 45, # 8 p. 1690 - 1696

146464-92-8 ~% 1445586-43-5 146464-93-9

文献：PLUS CHEMICALS S.A.; TEVA PHARMACEUTICALS USA, INC.; TISENI, Paolo, Simone; GALLUZZO, Christian; CANAVESI, Augusto; BILJAN, Tomislav Patent: WO2013/96800 A1, 2013 ; Location in patent: Page/Page column 17; 18 ;

52787-14-1 ~% 146464-93-9

文献：ALLOS THERAPEUTICS, INC. Patent: US2011/190305 A1, 2011 ;

52853-40-4 ~% 146464-93-9

文献：Vaidya, Chitra M.; Wright, Joel E.; Rosowsky, Andre Journal of Medicinal Chemistry, 2002 , vol. 45, # 8 p. 1690 - 1696

1571-08-0 ~% 146464-93-9

文献：AVRA LABORATORIES PRIVATE LIMITED; ALLA, Rama Rao Venkata; RAMARAO, Chandrashekar; MICHEL, Patrick Thomas; NITLIKAR, Lakshmikant Hanumanthrao; KALAM, Bhupathi Reddy; DUDUKA, Ramprasad Patent: WO2013/164856 A1, 2013 ;

76322-80-0 ~% 146464-93-9

文献：AVRA LABORATORIES PRIVATE LIMITED; ALLA, Rama Rao Venkata; RAMARAO, Chandrashekar; MICHEL, Patrick Thomas; NITLIKAR, Lakshmikant Hanumanthrao; KALAM, Bhupathi Reddy; DUDUKA, Ramprasad Patent: WO2013/164856 A1, 2013 ;

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