139442-01-6

139442-01-6结构式

中文名	4'-C-叠氮基尿苷
英文名	1-[(2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
英文别名	4’-alpha-C-azidouridine Uridine, 4'-C-azido 1-[(2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione (non-preferred name) 4'-alpha-Azidouridine 4’-alpha-Azidouridine, 1-(4’-Azido-beta-D-ribofuranosyl)uracil 4’-alpha-Azidouridine 1-(4'-Azido-beta-D-ribofuranosyl)uracil Uridine,4'-C-azido 1-((2R,3R,4S,5R)-5-Azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione 4'-C-azidouridine 4’-alpha-C-azidouridine,1-(4’-alpha-C-Azido-beta-D-ribofuranosyl)uracil 4'-azido-uridine 1-[(2R,3R,4S,5R)-5-Azido-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione 4'-AzU 4’-Azidouridine Uridine, 4'-azido 1-((2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

描述	4’-丙二氮丙啶(4’-氮丙啶)是尿苷类似物。尿苷具有潜在的抗癫痫作用,其类似物可用于研究抗惊厥和抗焦虑活性,以及开发新的抗高血压药物[1]。
相关类别	信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物研究领域 >> 其他
参考文献	[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.