5554-64-3

• 常用中文名：3-(二甲基氨基)-1-苯基丙-1-醇
• 常用英文名：3-dimethylamino-1-phenyl-propan-1-ol
• CAS号：5554-64-3
• 分子式：C₁₁H₁₇NO
• 分子量：179.25900
• 发布时间：2017-11-27 03:31:58
• 更新时间：2025-08-26 23:35:37

名称

• 中文名: 3-(二甲基氨基)-1-苯基丙-1-醇
• 英文名: 3-(Dimethylamino)-1-phenyl-1-propanol
• 中文别名: 3 - 二甲氨基-1 - 苯基 - 丙-1 - 醇; 3-二甲基氨基-1-苯基-1-丙醇; 3-(二甲基氨基)-1-苯基丙烷-1-醇; 阿托莫西汀杂质20; 托莫西汀杂质20
• 英文别名: 2-(1,1-Dimethyl-2-propenyl)-3-hydroxy-1,4-naphthalenedione; 3-(dimethylamino)-1-phenyl-propan-1-ol; 2-(1,1-dimethyl-2-propenyl)-3-hydroxy-1,4-naphthoquinone; 1-Propanol, 3-dimethylamino-1-phenyl; N,N-dimethyl-3-phenyl-3-hydroxy-propanamine; 2-(1,1-dimethylprop-2-enyl)-3-hydroxy-1,4-naphthoquinone; 1-Phenyl-3-(dimethylamino)-1-propanol; BenzeneMethanol, a-[2-(diMethylaMino)ethyl]; 2-(1,1-dimethylprop-2-enyl)-3-hydroxy-naphthalene-1.4-dione; Atomoxetine Impurity 20; 3-(DIMETHYLAMINO)-1-PHENYLPROPAN-1-OL(WXG00975); 2-hydroxy-3-(1,1-dimethylallyl)-1,4-naphthoquinone; 3-(Dimethylallyl)-2-hydroxy-1,4-naphthoquinone; α-[2-(Dimethylamino)ethyl]benzenemethanol; (+/-)-dimethyl(3-hydroxy-3-phenylpropyl)amine; 3-dimethylamino-1-phenyl-1-propanol; N,N-Dimethyl-3-hydroxy-3-phenylpropylamine; 3-Hydroxy-n,n-dimethyl-3-phenyl propylamine; USAF EL-80; Benzenemethanol, α-[2-(dimethylamino)ethyl]

物化性质

• 密度: 1.011g/cm3
• 沸点: 284.4ºC at 760mmHg
• 分子式: C₁₁H₁₇NO
• 分子量: 179.25900
• 闪点: 99.8ºC
• 精确质量: 179.13100
• PSA: 23.47000
• LogP: 1.67170

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UB3675000 CHEMICAL NAME : 1-Propanol, 3-dimethylamino-1-phenyl- CAS REGISTRY NUMBER : 5554-64-3 LAST UPDATED : 199012 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C11-H17-N-O MOLECULAR WEIGHT : 179.29 WISWESSER LINE NOTATION : QYR&2N1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

安全

• 海关编码: 2922199090

合成路线

3506-36-3 ~92% 5554-64-3

文献：Kellogg, Richard M.; Nieuwenhuijzen, Jose W.; Pouwer; Vries, Ton R.; Broxterman, Quirinus B.; Grimbergen, Reinier F.P.; Kaptein, Bernard; La Crois, Rene M.; De Wever, Ellen; Zwaagstra, Karen; Van Der Laan, Alexander C. Synthesis, 2003 , # 10 p. 1626 - 1638

879-72-1 ~91% 5554-64-3

文献：Arava, Veera Reddy; Malreddy, Sashibhushan; Thummala, Sreenivasulu Reddy Synthetic Communications, 2012 , vol. 42, # 24 p. 3545 - 3552,8

87968-05-6 ~0% 5554-64-3 1201-56-5

文献：Suzuki, Kunio; Okano, Koji; Nakai, Kiyomitsu; Terao, Yoshiyasu; Sekiya, Minoru Synthesis, 1983 , # 9 p. 723 - 725

98-86-2 ~% 5554-64-3

文献：Miyano, Sotaro; Lu, Linda D.-L.; Viti, Steven M.; Sharpless, K. Barry Journal of Organic Chemistry, 1985 , vol. 50, # 22 p. 4350 - 4360

18871-71-1 ~% 5554-64-3

文献：Suzuki, Kunio; Okano, Koji; Nakai, Kiyomitsu; Terao, Yoshiyasu; Sekiya, Minoru Synthesis, 1983 , # 9 p. 723 - 725

292638-84-7 30438-74-5 ~% 30457-88-6 5554-64-3 详细

文献：Manninen, Kalle; Karjalainen, Aira Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 3 p. 190 - 195

18776-12-0 124-40-3 ~% 5554-64-3

文献：Fourneau Chem. Zentralbl., 1907 , vol. 78, # II p. 1087

879-72-1 7732-18-5 ~% 5554-64-3

文献：Mannich; Heilner Chemische Berichte, 1922 , vol. 55, p. 362

60-29-7 7732-18-5 3506-36-3 ~% 5554-64-3

文献：Mannich; Heilner Chemische Berichte, 1922 , vol. 55, p. 362

上下游产品

上游产品  9
3506-36-3 879-72-1 87968-05-6 98-86-2
292638-84-7 30438-74-5 18776-12-0 124-40-3
7732-18-5
下游产品  3
79130-51-1 5424-50-0 56225-81-1

海关

海关编码	2922199090
中文概述	2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%