186668-40-6

• 常用中文名：5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione
• 常用英文名：5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione
• CAS号：186668-40-6
• 分子式：C₂₁H₁₈N₂O₄
• 分子量：362.37900
• 发布时间：2017-08-24 20:46:34
• 更新时间：2024-01-02 22:36:12

名称

• 英文名: 5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione
• 英文别名: homo-camptothecin; 3H,15H-Oxepino(3',4':6,7)indolizino(1,2-b)quinoline-3,15-dione,5-ethyl-1,4,5,13-tetrahydro-5-hydroxy; (+/-)-E-Homocamptothecin; UNII-33SH2P87CX; rac-homocamptothecin; 5-ethyl-1,4,5,13-tetrahydro-5-hydroxy-3H,15H-oxepino[3',4': 6,7]indolizino[1,2-b]quinoline-3,15-dione

物化性质

• 分子式: C₂₁H₁₈N₂O₄
• 分子量: 362.37900
• 精确质量: 362.12700
• PSA: 81.42000
• LogP: 2.46970

合成路线

186668-38-2 ~70% 186668-40-6

文献：Lavergne, Olivier; Lesueur-Ginot, Laurence; Rodas, Francesc Pla; Bigg, Dennis C. H. Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 17 p. 2235 - 2238

618-36-0 186668-41-7 ~% 186668-40-6

文献：Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.) Patent: US6815546 B2, 2004 ;

7689-03-4 ~% 186668-40-6

文献：Li, Di-Zao; Wang, Cun-Ying; Liu, Rui-Hua; Wang, Yan-Ming; Ji, Teng-Fei; Li, Yu-Rong; Pan, Xian-Dao Journal of Asian Natural Products Research, 2013 , vol. 15, # 11 p. 1179 - 1188

210563-62-5 ~% 186668-40-6

文献：Li, Di-Zao; Wang, Cun-Ying; Liu, Rui-Hua; Wang, Yan-Ming; Ji, Teng-Fei; Li, Yu-Rong; Pan, Xian-Dao Journal of Asian Natural Products Research, 2013 , vol. 15, # 11 p. 1179 - 1188

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