59641-32-6

• 常用中文名：2-chloro-3-ethoxynaphthalene-1,4-dione
• 常用英文名：2-chloro-3-ethoxynaphthalene-1,4-dione
• CAS号：59641-32-6
• 分子式：C₁₂H₉ClO₃
• 分子量：236.65100
• 发布时间：2016-02-07 22:46:28
• 更新时间：2024-01-10 18:17:56

名称

• 英文名: 2-chloro-3-ethoxynaphthalene-1,4-dione
• 英文别名: 1,4-NAPHTHOQUINONE,2-CHLORO-3-ETHOXY; 2-Chloro-3-ethoxy-1,4-naphthalenedione

物化性质

• 密度: 1.35g/cm3
• 沸点: 378.8ºC at 760 mmHg
• 分子式: C₁₂H₉ClO₃
• 分子量: 236.65100
• 闪点: 164.2ºC
• 精确质量: 236.02400
• PSA: 43.37000
• LogP: 2.55250
• 折射率: 1.588

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QL7472700 CHEMICAL NAME : 1,4-Naphthoquinone, 2-chloro-3-ethoxy- CAS REGISTRY NUMBER : 59641-32-6 BEILSTEIN REFERENCE NO. : 2264718 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H9-Cl-O3 MOLECULAR WEIGHT : 236.66 WISWESSER LINE NOTATION : L66 BV EVJ CG DO2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 16 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,570,1983

合成路线

117-80-6 64-17-5 ~49% 59641-32-6

文献：Hodnett, Ernest M.; Wongwiechintana, Chinda; Dunn, William J.; Marrs, Pam Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 570 - 574

117-80-6 ~% 59641-32-6

文献：Gaertner Journal of the American Chemical Society, 1954 , vol. 76, p. 6150,6155

117-80-6 141-52-6 ~51% 59641-32-6 75235-99-3

文献：Lien, Jin-Cherng; Huang, Li-Jiau; Wang, Jih-Pyang; Teng, Che-Ming; Lee, Kuo-Hsiung; Kuo, Sheng-Chu Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 6 p. 1181 - 1187

75-03-6 ~% 59641-32-6

文献：Fieser Journal of the American Chemical Society, 1926 , vol. 48, p. 2927,2929 Journal of the American Chemical Society, 1928 , vol. 50, p. 439,443

117-80-6 64-17-5 2483-57-0 ~11% 1200406-00-3 详细

文献：Santos, Maria M.M.; Faria, Natalia; Iley, Jim; Coles, Simon J.; Hursthouse, Michael B.; Martins, M. Luz; Moreira, Rui Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 193 - 195

117-80-6 64-17-5 2885-00-9 ~14% 1243625-72-0 详细

文献：Sayil, Cigdem; Ibis, Cemil Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 5 p. 1233 - 1236