153244-86-1

• 常用中文名：(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(naphthalen-2-ylmethyl)-1,3-diazepan-2-one
• 常用英文名：(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(naphthalen-2-ylmethyl)-1,3-diazepan-2-one
• CAS号：153244-86-1
• 分子式：C₄₁H₃₈N₂O₃
• 分子量：606.75200
• 发布时间：2016-12-22 16:10:43
• 更新时间：2024-01-23 17:42:17

名称

• 英文名: (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(naphthalen-2-ylmethyl)-1,3-diazepan-2-one
• 英文别名: 2H-1,3-Diazepin-2-one,hexahydro-5,6-dihydroxy-1,3-bis(2-naphthalenylmethyl)-4,7-bis(phenylmethyl)-,(4R,5S,6S,7R); [4R-(4ALPHA,5ALPHA,6BETA,7BETA)]-HEXAHYDRO-5,6-DIHYDROXY-1,3-BIS[2-NAPHTHYL-METHYL]-4,7-BIS(PHENYLMETHYL)-2H-1,3-DIAZEPIN-2-ONE; 1hvr; XK263; XK2

物化性质

• 密度: 1.268g/cm3
• 沸点: 819ºC at 760mmHg
• 分子式: C₄₁H₃₈N₂O₃
• 分子量: 606.75200
• 闪点: 449.1ºC
• 精确质量: 606.28800
• PSA: 64.01000
• LogP: 7.25100
• 蒸汽压: 2.24E-28mmHg at 25°C
• 折射率: 1.705

合成路线

1054639-78-9 ~% 153244-86-1

文献：Hodge, C. Nicholas; Lam, Patrick Y. S.; Eyermann, Charles J.; Jadhav, Prabhakar K.; Ru; Fernandez, Christina H.; De Lucca, George V.; Chang, Chong-Hwan; Kaltenbach III, Robert F.; Holler, Edward R.; Woerner, Francis; Daneker, Wayne F.; Emmett, George; Calabrese, Joseph C.; Aldrich, Paul E. Journal of the American Chemical Society, 1998 , vol. 120, # 19 p. 4570 - 4581

153181-22-7 ~% 153244-86-1

文献：Lam, Patrick Y. S.; Ru, Yu; Jadhav, Prabhakar K.; Aldrich, Paul E.; DeLucca, George V.; Eyermann, Charles J.; Chang, Chong-Hwan; Emmett, George; Holler, Edward R.; Daneker, Wayne F.; Li, Liangzhu; Confalone, Pat N.; McHugh, Robert J.; Han, Qi; Li, Renhua; Markwalder, Jay A.; Seitz, Steven P.; Sharpe, Thomas R.; Bacheler, Lee T.; Rayner, Marlene M.; Klabe, Ronald M.; Shum, Linyee; Winslow, Dean L.; Kornhauser, David M.; Jackson, David A.; Erickson-Viitanen, Susan; Hodge, C. Nicholas Journal of Medicinal Chemistry, 1996 , vol. 39, # 18 p. 3514 - 3525

939-26-4 ~% 153244-86-1

文献：Hodge, C. Nicholas; Lam, Patrick Y. S.; Eyermann, Charles J.; Jadhav, Prabhakar K.; Ru; Fernandez, Christina H.; De Lucca, George V.; Chang, Chong-Hwan; Kaltenbach III, Robert F.; Holler, Edward R.; Woerner, Francis; Daneker, Wayne F.; Emmett, George; Calabrese, Joseph C.; Aldrich, Paul E. Journal of the American Chemical Society, 1998 , vol. 120, # 19 p. 4570 - 4581

58917-85-4 ~% 153244-86-1

文献：Lam, Patrick Y. S.; Ru, Yu; Jadhav, Prabhakar K.; Aldrich, Paul E.; DeLucca, George V.; Eyermann, Charles J.; Chang, Chong-Hwan; Emmett, George; Holler, Edward R.; Daneker, Wayne F.; Li, Liangzhu; Confalone, Pat N.; McHugh, Robert J.; Han, Qi; Li, Renhua; Markwalder, Jay A.; Seitz, Steven P.; Sharpe, Thomas R.; Bacheler, Lee T.; Rayner, Marlene M.; Klabe, Ronald M.; Shum, Linyee; Winslow, Dean L.; Kornhauser, David M.; Jackson, David A.; Erickson-Viitanen, Susan; Hodge, C. Nicholas Journal of Medicinal Chemistry, 1996 , vol. 39, # 18 p. 3514 - 3525

63219-70-5 ~% 153244-86-1

文献：Lam, Patrick Y. S.; Ru, Yu; Jadhav, Prabhakar K.; Aldrich, Paul E.; DeLucca, George V.; Eyermann, Charles J.; Chang, Chong-Hwan; Emmett, George; Holler, Edward R.; Daneker, Wayne F.; Li, Liangzhu; Confalone, Pat N.; McHugh, Robert J.; Han, Qi; Li, Renhua; Markwalder, Jay A.; Seitz, Steven P.; Sharpe, Thomas R.; Bacheler, Lee T.; Rayner, Marlene M.; Klabe, Ronald M.; Shum, Linyee; Winslow, Dean L.; Kornhauser, David M.; Jackson, David A.; Erickson-Viitanen, Susan; Hodge, C. Nicholas Journal of Medicinal Chemistry, 1996 , vol. 39, # 18 p. 3514 - 3525

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