681482-81-5

• 常用中文名：4-(4-(4-三氟甲氧基)-苯氧基)哌啶-1-基)苯酚
• 常用英文名：4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol
• CAS号：681482-81-5
• 分子式：C₁₈H₁₈F₃NO₃
• 分子量：353.33600
• 发布时间：2018-11-25 08:37:47
• 更新时间：2024-01-09 09:26:10

名称

• 中文名: 4-(4-(4-三氟甲氧基)-苯氧基)哌啶-1-基)苯酚
• 英文名: 4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol
• 英文别名: ss-3227

物化性质

• 分子式: C₁₈H₁₈F₃NO₃
• 分子量: 353.33600
• 精确质量: 353.12400
• PSA: 41.93000
• LogP: 4.40360
• 储存条件: 2-8°C

合成路线

1083099-55-1 ~99% 681482-81-5

文献：OTSUKA PHARMACEUTICAL CO., LTD. Patent: WO2008/140090 A1, 2008 ; Location in patent: Page/Page column 42-43 ;

637-88-7 287952-67-4 ~89% 681482-81-5

文献：OTSUKA PHARMACEUTICAL CO., LTD. Patent: WO2005/92832 A1, 2005 ; Location in patent: Page/Page column 48-49 ;

681482-80-4 ~91% 681482-81-5

文献：Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860

866109-93-5 ~96% 681482-81-5

文献：OTSUKA PHARMACEUTICAL CO., LTD. Patent: WO2008/140090 A1, 2008 ; Location in patent: Page/Page column 34-35; 36-37 ;

36603-49-3 ~% 681482-81-5

文献：Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860

287952-67-4 ~% 681482-81-5

文献：Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860

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