853296-94-3

• 常用中文名：3-[(4-甲基-1-哌嗪基)甲基]-5-(三氟甲基)苯胺
• 常用英文名：3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)aniline
• CAS号：853296-94-3
• 分子式：C₁₃H₁₈F₃N₃
• 分子量：273.29700
• 发布时间：2018-12-03 20:20:22
• 更新时间：2025-09-11 08:58:26

名称

• 中文名: 3-[(4-甲基哌嗪-1-基)甲基]-5-(三氟-甲基)苯胺
• 英文名: 3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)aniline
• 英文别名: Benzenamine,3-[(4-methyl-1-piperazinyl)methyl]-5-(trifluoromethyl); 3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)-benzenamine; 3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoro-methyl)aniline

物化性质

• 密度: 1.227±0.06 g/cm3
• 沸点: 333.7±42.0 °C
• 分子式: C₁₃H₁₈F₃N₃
• 分子量: 273.29700
• 精确质量: 273.14500
• PSA: 32.50000
• LogP: 2.49200
• 储存条件: 2-8°C

合成路线

853296-96-5 ~51% 853296-94-3

文献：Oguro, Yuya; Miyamoto, Naoki; Takagi, Terufumi; Okada, Kengo; Awazu, Yoshiko; Miki, Hiroshi; Hori, Akira; Kamiyama, Keiji; Imamura, Shinichi Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 20 p. 7150 - 7163

853296-95-4 ~% 853296-94-3

文献：AMGEN INC. Patent: WO2005/113494 A2, 2005 ; Location in patent: Page/Page column 107 ; WO 2005/113494 A2

632353-50-5 ~% 853296-94-3

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2007/119055 A1, 2007 ; Location in patent: Page/Page column 37 ; WO 2007/119055 A1

942076-92-8 ~% 853296-94-3

文献：CROWN BIOSCIENCE INC. (TAICANG); ZHANG, Deyi; ZHANG, Ruihao; ZHONG, Boyu; SHIH, Chuan Patent: WO2014/418 A1, 2014 ; Location in patent: Page/Page column 81 ;

133587-82-3 ~% 853296-94-3

文献：CROWN BIOSCIENCE INC. (TAICANG); ZHANG, Deyi; ZHANG, Ruihao; ZHONG, Boyu; SHIH, Chuan Patent: WO2014/418 A1, 2014 ;