59455-95-7

• 常用中文名：4-氯-2-(2-噻吩)喹唑啉
• 常用英文名：4-CHLORO-2-(2-THIENYL)QUINAZOLINE
• CAS号：59455-95-7
• 分子式：C₁₂H₇ClN₂S
• 分子量：246.71500
• 发布时间：2018-07-05 18:17:33
• 更新时间：2024-01-08 12:08:03

名称

• 中文名: 4-氯-2-(2-噻吩)喹唑啉
• 英文名: 4-chloro-2-thiophen-2-ylquinazoline
• 英文别名: HMS1717I20; 4-chloro-2-(2'-thienyl)quinazoline; 4-chloro-2-(thiophen-2-yl)quinazoline; 4-chloro-2-thien-2-ylquinazoline

物化性质

• 分子式: C₁₂H₇ClN₂S
• 分子量: 246.71500
• 精确质量: 246.00200
• PSA: 54.02000
• LogP: 4.01170

合成路线

26059-85-8 ~97% 59455-95-7

文献：Signal Pharmaceuticals, Inc. Patent: US5939421 A1, 1999 ;

5271-67-0 ~% 59455-95-7

文献：Palanki, Moorthy S. S.; Erdman, Paul E.; Ren, Minghuan; Suto, Mark; Bennett, Brydon L.; Manning, Anthony; Ransone, Lynn; Spooner, Cheryl; Desai, Sonal; Ow, Arnie; Totsuka, Ryuichi; Tsao, Peter; Toriumi, Wataru Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 4077 - 4080

59490-98-1 ~% 59455-95-7

文献：Lee; Konishi; Yu; Miskowski; Riviello; Macina; Frierson; Kondo; Sugitani; Sircar; Blazejewski Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3547 - 3557

28144-70-9 ~% 59455-95-7

文献：Lee; Konishi; Yu; Miskowski; Riviello; Macina; Frierson; Kondo; Sugitani; Sircar; Blazejewski Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3547 - 3557

118-92-3 ~% 59455-95-7

文献：Palanki, Moorthy S. S.; Erdman, Paul E.; Ren, Minghuan; Suto, Mark; Bennett, Brydon L.; Manning, Anthony; Ransone, Lynn; Spooner, Cheryl; Desai, Sonal; Ow, Arnie; Totsuka, Ryuichi; Tsao, Peter; Toriumi, Wataru Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 4077 - 4080

527-72-0 ~% 59455-95-7

文献：Marugan, Juan J.; Zheng, Wei; Motabar, Omid; Southall, Noel; Goldin, Ehud; Westbroek, Wendy; Stubblefield, Barbara K.; Sidransky, Ellen; Aungst, Ronald A.; Lea, Wendy A.; Simeonov, Anton; Leister, William; Austin, Christopher P. Journal of Medicinal Chemistry, 2011 , vol. 54, # 4 p. 1033 - 1058

26060-06-0 ~% 59455-95-7

文献：Palanki, Moorthy S. S.; Erdman, Paul E.; Ren, Minghuan; Suto, Mark; Bennett, Brydon L.; Manning, Anthony; Ransone, Lynn; Spooner, Cheryl; Desai, Sonal; Ow, Arnie; Totsuka, Ryuichi; Tsao, Peter; Toriumi, Wataru Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 4077 - 4080

33405-06-0 ~% 59455-95-7

文献：Palanki, Moorthy S. S.; Erdman, Paul E.; Ren, Minghuan; Suto, Mark; Bennett, Brydon L.; Manning, Anthony; Ransone, Lynn; Spooner, Cheryl; Desai, Sonal; Ow, Arnie; Totsuka, Ryuichi; Tsao, Peter; Toriumi, Wataru Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 4077 - 4080