N-[4-fluoro-3-(morpholine-4-sulfonyl)phenyl]-1-phenyl-1H-pyrazole-4-carboxamide

• 常用名: N-[4-fluoro-3-(morpholine-4-sulfonyl)phenyl]-1-phenyl-1H-pyrazole-4-carboxamide
• 英文名: N-[4-fluoro-3-(morpholine-4-sulfonyl)phenyl]-1-phenyl-1H-pyrazole-4-carboxamide
• CAS号: 1007648-66-9
• 分子量: 430.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₉FN₄O₄S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[4-fluoro-3-(morpholine-4-sulfonyl)phenyl]-1-phenyl-1H-pyrazole-4-carboxamide

物理化学性质

• 分子式: C₂₀H₁₉FN₄O₄S
• 分子量: 430.5
• InChIKey: WACWBLDRQWZGDZ-UHFFFAOYSA-N
• SMILES: C1COCCN1S(=O)(=O)C2=C(C=CC(=C2)NC(=O)C3=CN(N=C3)C4=CC=CC=C4)F

靶点实验

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实验名称：Cytotoxicity against HEK293T cells expressing FXR and beta-lactamase genes assessed a... 来源：ChEMBL 靶标：HEK-293T External Id：CHEMBL3269922

实验名称：Antagonist activity at human GST-tagged FXR at 13.3 uM after 20 mins by TR-FRET assay... 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL3269929

实验名称：Agonist activity at human GST-tagged FXR after 20 mins by TR-FRET assay 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL3270291

实验名称：Antagonist activity at human GST-tagged FXR after 20 mins by TR-FRET assay 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL3269919

实验名称：Inhibition of GW4064-induced transactivation of FXR (unknown origin) expressed in HEK... 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL3269921

实验名称：Inhibition of GW4064-induced transactivation of FXR (unknown origin) expressed in HEK... 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL3269920

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