Largazole

• 常用名: Largazole
• 英文名: Largazole
• CAS号: 1009815-87-5
• 分子量: 622.86300
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₄₂N₄O₅S₃
• 熔点: N/A
• 闪点: N/A

Largazole名称

• 英文名: (+)-largazole

Largazole物理化学性质

• 分子式: C₂₉H₄₂N₄O₅S₃
• 分子量: 622.86300
• 精确质量: 622.23200
• PSA: 212.64000
• LogP: 5.02170
• InChIKey: AXESYCSCGBQJBL-UAOHEDPGSA-N
• SMILES: CCCCCCCC(=O)SCCC=CC1CC(=O)NCc2nc(cs2)C2=NC(C)(CS2)C(=O)NC(C(C)C)C(=O)O1

Largazole靶点实验

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实验名称：Upregulation of p21 mRNA expression in human A549 cells at 0.1 uM after 12 hrs by RT-... 来源：ChEMBL 靶标：A549 External Id：CHEMBL2445400

实验名称：Inhibition of HDAC2 (unknown origin) using MAZ1600 and MAZ1675 as substrate assessed ... 来源：ChEMBL 靶标：Histone deacetylase 2 External Id：CHEMBL2437618

实验名称：Cell cycle arrest in human NB4 cells assessed as increase in accumulation at pre-G1 p... 来源：ChEMBL 靶标：NB-4 External Id：CHEMBL1177024

实验名称：Downregulation of p21 protein expression in human A549 cells at 0.1 uM after 1 hr by ... 来源：ChEMBL 靶标：A549 External Id：CHEMBL2445399

实验名称：Inhibition of HDAC3 (unknown origin) using MAZ1600 and MAZ1675 as substrate assessed ... 来源：ChEMBL 靶标：Histone deacetylase 3 External Id：CHEMBL2437617

实验名称：Cell cycle arrest in human NB4 cells assessed as increase in accumulation at pre-G1 p... 来源：ChEMBL 靶标：NB-4 External Id：CHEMBL1177023

实验名称：Upregulation of p21 protein expression in human A549 cells at 0.1 uM after 6 hrs by W... 来源：ChEMBL 靶标：A549 External Id：CHEMBL2445398

实验名称：Inhibition of HDAC6 (unknown origin) using MAZ1600 and MAZ1675 as substrate assessed ... 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL2437616

实验名称：Inhibition of HDAC-1 in human A549 cells assessed as recruitment of p21 promoter to a... 来源：ChEMBL 靶标：Histone deacetylase 1 External Id：CHEMBL2445153

实验名称：Upregulation of p27 protein expression in human A549 cells at 0.1 uM after 12 hrs by ... 来源：ChEMBL 靶标：A549 External Id：CHEMBL2445404

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Largazole英文别名

• MK-571,NA SALT
• MK-571 SODIUM SALT
• (3-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)((3-dimethylamino-3-oxopropyl)thio)methyl)thiopropanoic acid
• 3-[[[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid
• (+)-L-660,711
• MK-571 NA
• Largazole
• MFCD18074512