2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-8-[(1r,4r)-4-hydroxycyclohexyl]-7H,8H-pyrido[2,3-d]pyrimidin-7-one,trans

• 常用名: 2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-8-[(1r,4r)-4-hydroxycyclohexyl]-7H,8H-pyrido[2,3-d]pyrimidin-7-one,trans
• 英文名: 2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-8-[(1r,4r)-4-hydroxycyclohexyl]-7H,8H-pyrido[2,3-d]pyrimidin-7-one,trans
• CAS号: 1013099-42-7
• 分子量: 381.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₃N₅O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-8-[(1r,4r)-4-hydroxycyclohexyl]-7H,8H-pyrido[2,3-d]pyrimidin-7-one,trans

物理化学性质

• 分子式: C₂₀H₂₃N₅O₃
• 分子量: 381.4
• InChIKey: FETTYQBQNFSCDZ-UHFFFAOYSA-N
• SMILES: CC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCC(CC3)O)C4=CN=C(C=C4)OC

靶点实验

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实验名称：Kinetic solubility of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL3225916

实验名称：Biochemical Assay from US Patent US8633204: "4-methylpyridopyrimidinone compounds" 来源：BindingDB 靶标：N/A External Id：BindingDB_6173_1

实验名称：Drug metabolism in iv dosed rat plasma assessed as 2-amino-8-((trans)-4-hydroxycycloh... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3225925

实验名称：Drug metabolism in po dosed mouse plasma assessed as 2-amino-8-((trans)-4-hydroxycycl... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3225927

实验名称：Drug metabolism in iv dosed rat plasma assessed as 2-amino-8-((cis)-4-hydroxycyclohex... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3225926

实验名称：Inhibition of recombinant mTOR (unknown origin) assessed as GFP-4E-BP1 substrate phos... 来源：ChEMBL 靶标：Serine/threonine-protein kinase mTOR External Id：CHEMBL3227715

实验名称：Drug metabolism in po dosed mouse plasma assessed as 2-amino-8-((cis)-4-hydroxycycloh... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3225928

实验名称：Inhibition of mouse PI3K alpha expressed in insect cells coexpressing p85 subunit ass... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL3227714

实验名称：Metabolic stability in human liver microsomes assessed as extraction ratio 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3225915

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