Rock-in-32

• 常用名: Rock-in-32
• 英文名: Rock-in-32
• CAS号: 1013117-40-2
• 分子量: 402.28
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₇Cl₂N₃O₂
• 熔点: N/A
• 闪点: N/A

Rock-in-32用途

ROCK-IN-32是一种有效的Rho激酶抑制剂。

Rock-in-32名称

• 英文名: ROCK-IN-32

Rock-in-32生物活性

• 描述: ROCK-IN-32是一种有效的Rho激酶抑制剂。
• 参考文献: 1. Zhou ZY, Huang B, Li S, Huang XH, Tang JY, Kwan YW, Hoi PM, Lee SM. Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish. Toxicol Appl Pharmacol. 2018 May 4;350:32-42. doi: 10.1016/j.taap.2018.04.037. [Epub ahead of print] PubMed PMID: 29730311.

Rock-in-32物理化学性质

• 分子式: C₂₀H₁₇Cl₂N₃O₂
• 分子量: 402.28
• InChIKey: XBFAFSAUQFDEOK-JKSUJKDBSA-N
• SMILES: O=C(Nc1cc2cc[nH]c(=O)c2cc1Cl)C1CNCC1c1ccc(Cl)cc1

Rock-in-32靶点实验

查看更多实验

实验名称：Half life in human liver microsomes at 1 mg/ml 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1120083

实验名称：Vasorelaxant activity in rat aortic ring assessed as inhibition of phenylephrine-indu... 来源：ChEMBL 靶标：Aorta External Id：CHEMBL1120082

实验名称：Inhibition of ROCK2 by luciferase based ATP detection assay 来源：ChEMBL 靶标：Rho-associated protein kinase 2 External Id：CHEMBL1120081

实验名称：Human Rho associated coiled-coil containing protein kinase 2 (Rho kinase) 来源：IUPHAR-DB 靶标：Rho associated coiled-coil containing protein kinase 2 (Rho kinase) [Homo sapiens] External Id：1504_Human

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