PDM11

• 常用名: PDM11
• 英文名: PDM11
• CAS号: 1032508-03-4
• 分子量: 274.742
• 密度: 1.2±0.1 g/cm3
• 沸点: 409.1±35.0 °C at 760 mmHg
• 分子式: C₁₆H₁₅ClO₂
• 熔点: N/A
• 闪点: 155.2±21.1 °C

PDM11用途

PDM11 是抗氧化剂白藜芦醇的衍生物。PDM11 对辐射分解产生的羟基自由基引发的亚油酸胶束氧化没有明显的保护作用。PDM11 在白藜芦醇活性测定中不活跃。

PDM11名称

• 英文名: 1-[(E)-2-(4-Chlorophenyl)vinyl]-3,5-dimethoxybenzene

PDM11生物活性

• 描述: PDM11 是抗氧化剂白藜芦醇的衍生物。PDM11 对辐射分解产生的羟基自由基引发的亚油酸胶束氧化没有明显的保护作用。PDM11 在白藜芦醇活性测定中不活跃。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Kondratyuk TP, et al. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Mol Nutr Food Res. 2011;55(8):1249-1265.

  [2]. Rhayem Y, et al. Chain-breaking activity of resveratrol and piceatannol in a linoleate micellar model. Chem Phys Lipids. 2008;155(1):48-56.

PDM11物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 409.1±35.0 °C at 760 mmHg
• 分子式: C₁₆H₁₅ClO₂
• 分子量: 274.742
• 闪点: 155.2±21.1 °C
• 精确质量: 274.076050
• PSA: 18.46000
• LogP: 5.19
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.622
• 储存条件: -20°C，密闭，干燥

PDM11靶点实验

查看更多实验

实验名称：Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of NO r... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5329985

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Stability of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL3830133

实验名称：Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of NO p... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5329983

实验名称：Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as NO ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5329981

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell survival rate at 50 uM by ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5329979

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

实验名称：Cytotoxicity against human Caco-2 cells after 3 days by [3H]thymidine incorporation a... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL1248459

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PDM11英文别名

• trans-4'-chloro-3,5-dimethoxystilbene
• 1-[(E)-2-(4-Chlorophenyl)vinyl]-3,5-dimethoxybenzene
• 3,5-dimethoxyl-4'-chloro-trans-stilbene