5-(6-(2-Methoxypropan-2-yl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

• 常用名: 5-(6-(2-Methoxypropan-2-yl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine
• 英文名: 5-(6-(2-Methoxypropan-2-yl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine
• CAS号: 1033740-29-2
• 分子量: 386.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₂N₆O₂S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 5-(6-(2-Methoxypropan-2-yl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

物理化学性质

• 分子式: C₁₈H₂₂N₆O₂S
• 分子量: 386.5
• InChIKey: BRCOIQMZYMWNIS-UHFFFAOYSA-N
• SMILES: COC(C)(C)c1cc2nc(-c3cnc(N)nc3)nc(N3CCOCC3)c2s1

靶点实验

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实验名称：Efflux ratio of apparent permeability from basolateral to apical over apical to basol... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2185839

实验名称：Inhibition of human recombinant mTOR (1360 to 2549 residues) expressed in insect cell... 来源：ChEMBL 靶标：Serine/threonine-protein kinase mTOR External Id：CHEMBL3816167

实验名称：Inhibition of PI3Kalpha in PTEN deficient human U87MG cells xenografted in NCr nude m... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2185131

实验名称：Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL3816166

实验名称：Ratio of unbound fraction in CD1 mouse brain to plasma at 25 mg/kg, po after 6 hrs by... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3816171

实验名称：Antitumor activity against PTEN deficient human U87MG cells xenografted in NCr nude m... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2185828

实验名称：Efflux ratio of apparent permeability from basolateral to apical over apical to basol... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3816170

实验名称：Efflux ratio of apparent permeability from basolateral to apical over apical to basol... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3816169

实验名称：Antiproliferative activity against human PC3 cells after 3 days by CellTitre-Glo assa... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3816168

实验名称：Plasma protein binding in CD-1 mouse 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2186310

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