8-(5-(4-ethylpiperazin-1-yl)-2-(trifluoromethoxy)phenylamino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

• 常用名: 8-(5-(4-ethylpiperazin-1-yl)-2-(trifluoromethoxy)phenylamino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide
• 英文名: 8-(5-(4-ethylpiperazin-1-yl)-2-(trifluoromethoxy)phenylamino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide
• CAS号: 1034616-20-0
• 分子量: 516.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₇F₃N₈O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-(5-(4-ethylpiperazin-1-yl)-2-(trifluoromethoxy)phenylamino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

物理化学性质

• 分子式: C₂₄H₂₇F₃N₈O₂
• 分子量: 516.5
• InChIKey: JKMYPJAZMANXBX-UHFFFAOYSA-N
• SMILES: CCN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1

靶点实验

查看更多实验

实验名称：Inhibition of PLK1 来源：ChEMBL 靶标：Serine/threonine-protein kinase PLK1 External Id：CHEMBL1272694

实验名称：Inhibition of PLK2 来源：ChEMBL 靶标：Serine/threonine-protein kinase PLK2 External Id：CHEMBL1272695

实验名称：Inhibition of PLK3 来源：ChEMBL 靶标：Serine/threonine-protein kinase PLK3 External Id：CHEMBL1272696

实验名称：Solubility of the compound at pH 7 来源：ChEMBL 靶标：N/A External Id：CHEMBL1272697

实验名称：Inhibition of CDK2/Cyclin A 来源：ChEMBL 靶标：Cyclin-A2 External Id：CHEMBL1272698

实验名称：Antiproliferative activity against human A2780 cells after 72 hrs by CellTiter-Glo as... 来源：ChEMBL 靶标：A2780 External Id：CHEMBL1272699

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