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3-(2-hydroxyethyl)-2-methylquinazolin-4-one

更新时间:2025-09-02 12:08:42

3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式
3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式
委托求购
常用名 3-(2-hydroxyethyl)-2-methylquinazolin-4-one 英文名 3-(2-hydroxyethyl)-2-methylquinazolin-4-one
CAS号 10376-59-7 分子量 204.22500
密度 1.26g/cm3 沸点 388.4ºC at 760mmHg
分子式 C11H12N2O2 熔点 N/A
MSDS N/A 闪点 188.7ºC

 名称

英文名 3-(2-hydroxyethyl)-2-methylquinazolin-4-one
英文别名 更多

 物理化学性质

密度 1.26g/cm3
沸点 388.4ºC at 760mmHg
分子式 C11H12N2O2
分子量 204.22500
闪点 188.7ºC
精确质量 204.09000
PSA 55.12000
LogP 0.69720
InChIKey JRXGAWVXJUVHTD-UHFFFAOYSA-N
SMILES Cc1nc2ccccc2c(=O)n1CCO
蒸汽压 9.98E-07mmHg at 25°C
折射率 1.617

 合成线路

~97%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式

3-(2-hydroxyeth...

10376-59-7

文献:DR.REDDY'S LABORATORIES LTD; DR.REDDY'S LABORATORIES LTD Patent: WO2006/29075 A2, 2006 ; Location in patent: Page/Page column 22 ; WO 2006/029075 A2

~%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式

3-(2-hydroxyeth...

10376-59-7

文献:University of California; Yissum Research Development Company of the Hebrew University of Jerusalem; Biosignal LTD; Sugen, Inc.; Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V. Patent: US6331555 B1, 2001 ; US 6331555 B1

~85%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式

3-(2-hydroxyeth...

10376-59-7

文献:Khan, Mahmud Tareq Hassan; Khan, Rasool; Wuxiuer, Yimingjiang; Arfan, Mohammad; Ahmed, Manzoor; Sylte, Ingebrigt Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 12 p. 4317 - 4327

~36%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式

3-(2-hydroxyeth...

10376-59-7

文献:Dunn, A. D.; Kinnear, K. I.; Norrie, R.; Ringan, N.; Martin, D. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 175 - 180

~52%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式

3-(2-hydroxyeth...

10376-59-7

文献:Jampilek, Josef; Musiol, Robert; Finster, Jacek; Pesko, Matus; Carroll, James; Kralova, Katarina; Vejsova, Marcela; O'Mahony, Jim; Coffey, Aidan; Dohnal, Jiri; Polanski, Jaroslaw Molecules, 2009 , vol. 14, # 10 p. 4246 - 4265

~%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one结构式

3-(2-hydroxyeth...

10376-59-7

文献:Buzas; Hoffmann Bulletin de la Societe Chimique de France, 1959 , p. 1889

 靶点实验

查看更多实验

实验名称:Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:HCMV UL50
External Id:HMS1262
实验名称:Identification of CBX7 inhibitors - Primary Alpha Screen
来源:15290
靶标:N/A
External Id:CBX7-Alpha-primary
实验名称:Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:ORF 73 [Human herpesvirus 8 type M]
External Id:HMS791
实验名称:High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS1303
实验名称:A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS979
实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:FBW7_ACT_ALPHA_1536_1X%ACT PRUN
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
External Id:MITF_INH_Alpha_1536_1X%INH PRUN
实验名称:Inhibition of Bacillus thermoproteolyticus thermolysin after 15 mins by microplate fl...
来源:ChEMBL
靶标:Thermolysin
External Id:CHEMBL1166366
实验名称:A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:Chain A, Poliovirus Polymerase With Gtp
External Id:HMS750
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 英文别名

2-methyl-3-hydroxyethyl quinazolin-4-one
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