氧洛哌丁胺

更新时间：2025-08-21 11:09:42

氧洛哌丁胺结构式	常用名	氧洛哌丁胺	英文名	Loperamide
	CAS号	106900-12-3	分子量	493.03700
	密度	N/A	沸点	N/A
	分子式	C₂₉H₃₃ClN₂O₃	熔点	N/A
	MSDS	N/A	闪点	N/A

氧洛哌丁胺用途

Loperamide oxide is a prodrug of the effective antidiarrheal loperamide.

中文名	氧洛哌丁胺
英文名	4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
英文别名	更多

分子式	C₂₉H₃₃ClN₂O₃
分子量	493.03700
精确质量	492.21800
PSA	69.97000
LogP	5.05940
水溶解性	Practically insoluble in water, freely soluble in alcohol and in methylene chloride.

氧洛哌丁胺毒性英文版

危险品运输编码	UN 2811 6.1 / PGIII
RTECS号	TM4960200

Loperamide oxide in acute diarrhoea: a double-blind, placebo-controlled trial. The Dutch Diarrhoea Trialists Group.

Aliment. Pharmacol. Ther. 9(4) , 441-6, (1995)

Loperamide is an established treatment of acute diarrhoea with only rare adverse reactions. The pro-drug loperamide oxide is converted to loperamide by anaerobic bacteria in the lower alimentary tract...

First-line treatment in acute non-dysenteric diarrhoea: clinical comparison of loperamide oxide, loperamide and placebo. UK Janssen Research Group of General Practitioners.

Br. J. Clin. Pract. 49(4) , 181-5, (1995)

The use of antimicrobial agents for the treatment of acute diarrhoea has become more common with the introduction of quinolone compounds, which are active against most types of bacterial pathogens. De...

Secretion of the antidiarrhoeal agent loperamide oxide in breast milk.

Eur. J. Clin. Pharmacol. 42(6) , 695-6, (1992)