8-((trans)-3-Fluoropiperidin-4-yloxy)-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinoline

• 常用名: 8-((trans)-3-Fluoropiperidin-4-yloxy)-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinoline
• 英文名: 8-((trans)-3-Fluoropiperidin-4-yloxy)-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinoline
• CAS号: 1070897-18-5
• 分子量: 436.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₅FN₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-((trans)-3-Fluoropiperidin-4-yloxy)-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinoline

物理化学性质

• 分子式: C₂₄H₂₅FN₄O₃
• 分子量: 436.5
• InChIKey: PPPOUAQYRUUFNJ-UHFFFAOYSA-N
• SMILES: COCCOc1ccn2c(-c3ccc4cccc(OC5CCNCC5F)c4n3)cnc2c1

靶点实验

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实验名称：Oral bioavailability in cynomolgus monkey at 30 mg/kg 来源：ChEMBL 靶标：Macaca fascicularis External Id：CHEMBL3111668

实验名称：Inhibition of cFMS (unknown origin) 来源：ChEMBL 靶标：Macrophage colony-stimulating factor 1 receptor External Id：CHEMBL3111863

实验名称：Inhibition of FLT3 (unknown origin) 来源：ChEMBL 靶标：Receptor-type tyrosine-protein kinase FLT3 External Id：CHEMBL3111864

实验名称：Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated ... 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL3111865

实验名称：Inhibition of CYP2C9 (unknown origin) 来源：ChEMBL 靶标：Cytochrome P450 2C9 External Id：CHEMBL3111866

实验名称：Inhibition of CYP1A2 (unknown origin) 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL3111867

实验名称：Clearance in rat at 1 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3111868

实验名称：Extraction ratio in human liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3111687

实验名称：Extraction ratio in cynomolgus monkey liver microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL3111688

实验名称：Extraction ratio in rat liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3111689

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