N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-{(2S)-1-[(6-fluoropyridin-3-yl)carbonyl]pyrrolidin-2-yl}pyrrolo[2,1-f][1,2,4]triazin-4-amine

• 常用名: N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-{(2S)-1-[(6-fluoropyridin-3-yl)carbonyl]pyrrolidin-2-yl}pyrrolo[2,1-f][1,2,4]triazin-4-amine
• 英文名: N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-{(2S)-1-[(6-fluoropyridin-3-yl)carbonyl]pyrrolidin-2-yl}pyrrolo[2,1-f][1,2,4]triazin-4-amine
• CAS号: 1072811-25-6
• 分子量: 432.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₁FN₈O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-{(2S)-1-[(6-fluoropyridin-3-yl)carbonyl]pyrrolidin-2-yl}pyrrolo[2,1-f][1,2,4]triazin-4-amine

物理化学性质

• 分子式: C₂₂H₂₁FN₈O
• 分子量: 432.5
• InChIKey: XXGADWBTSMHVDF-INIZCTEOSA-N
• SMILES: O=C(c1ccc(F)nc1)N1CCCC1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1

靶点实验

查看更多实验

实验名称：Permeability by PAMPA assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL1228262

实验名称：Experimentally measured binding affinity data (IC50) for protein-ligand complexes der... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-IC50 for protein-ligand complexes

实验名称：Inhibition of IGF1R in IGF1R-SAL cells 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL1228261

实验名称：Inhibition of IGF1R 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL1228260

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