(2R)-2-(5-Fluoropyridin-2-yl)-2-{[3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-yl]amino}ethanol

• 常用名: (2R)-2-(5-Fluoropyridin-2-yl)-2-{[3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-yl]amino}ethanol
• 英文名: (2R)-2-(5-Fluoropyridin-2-yl)-2-{[3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-yl]amino}ethanol
• CAS号: 1079274-96-6
• 分子量: 397.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₀FN₇O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (2R)-2-(5-Fluoropyridin-2-yl)-2-{[3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-yl]amino}ethanol

物理化学性质

• 分子式: C₁₉H₂₀FN₇O₂
• 分子量: 397.4
• InChIKey: CEDQYWYBSMPQAF-HNNXBMFYSA-N
• SMILES: CC(C)Oc1cc(-n2cnc3ccc(NC(CO)c4ccc(F)cn4)nc32)[nH]n1

靶点实验

查看更多实验

实验名称：Intrinsic clearance in rat hepatocytes assessed per million cells by LC/MS/MS analysi... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL2154691

实验名称：Clearance in Han Wistar rat at 10 mg/kg, po and 3 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2154692

实验名称：Inhibition of TrkA deletion mutant tyrosine phosphorylation in human MCF10A cells by ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2154690

实验名称：ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301363

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301365

实验名称：Amplified Luminescent Proximity Assay from US Patent US8486966: "9-(pyrazol-3-yl)-9H-... 来源：BindingDB 靶标：N/A External Id：BindingDB_5870_1

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301367

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301366

实验名称：Antitumor activity against 3T3 cells overexpressing constitutively active TRKA allogr... 来源：ChEMBL 靶标：NIH3T3 External Id：CHEMBL2155042

实验名称：Antitumor activity against 3T3 cells overexpressing constitutively active TRKA allogr... 来源：ChEMBL 靶标：NIH3T3 External Id：CHEMBL2155043

共19条，当前第1页，共2页

1

2